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Discover the hidden link that triggers chronic inflammation, the key mechanism behind autoimmune, cancer, heart disease, and more.

Join me and Dr. Tom Obryan in this eye-opening discussion as we delve into the million-dollar question: What is causing inflammation in your body?

Find answers and actionable insights to transform your health journey.

Your host, Nathan Crane, is a Certified Holistic Cancer Coach, Best-Selling Author, Inspirational Speaker, Cancer-Health Researcher and Educator, and 20X Award Winning Documentary Filmmaker with Over 15 Years in the Health Field.

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Audio Transcript

 

(This transcript was auto-generated so there may be some errors)

 

00:00:00:00 – 00:00:21:03
Nathan Crane
Dr. Tom, welcome to the podcast. So happy to have you here joining me. It’s been a minute since we’ve talked and you’re up to some amazing work as usual. So thanks for coming on. I’m excited to talk about it with you and reconnect with you. Talk about one of the things I want to talk about initially is autoimmune disease and dove deeply into that topic.

00:00:21:03 – 00:00:23:20
Nathan Crane
But yeah, welcome to the podcast.

00:00:24:13 – 00:00:26:08
Dr. Tom Obryan
Thank you so much. Pleasure to be with you again.

00:00:26:08 – 00:00:33:07
Nathan Crane
Nathan So what is at the root cause of all autoimmune diseases?

00:00:34:08 – 00:01:02:14
Dr. Tom Obryan
You know, that’s a really good question to start with because there’s a lot of people that say root cause medicine, you know, and they’re doing root causes and root causes that there is no root cause. There are multiple causes, but there’s a root mechanism in the development of chronic inflammatory diseases, whether it’s autoimmune or cancer, heart disease. And that root mechanism is inflammation.

00:01:03:06 – 00:01:41:07
Dr. Tom Obryan
It’s always inflammation. You know, the Centers for Disease Control tells us that 14 of the 15 top causes of death are chronic inflammatory diseases. It’s always inflammation, except for unintentional injuries in accident. Everything else is inflammation. And we all think that when you get diagnosed with something or when you start getting symptoms, you’ve begun to have a problem, know it’s been there for years already under the surface with this low grade chronic inflammation under the surface.

00:01:41:07 – 00:02:03:18
Dr. Tom Obryan
While you feel fine. You think you feel fine? Yeah. A little. A campaign once in a while. Yeah. I was tired yesterday afternoon. I needed a cup of coffee or, you know, our mind tries to rationalize why we have these little things we notice once in a while. But those are biomarkers of a cumulative inflammation in your body.

00:02:04:14 – 00:02:25:23
Dr. Tom Obryan
And here’s a basic concept. You pull it a chain, it always breaks it. The weakest link, always. It’s going to be one in the middle, the other. And it’s your heart, your brain, your liver, your kidneys, your weak link is determined by your genetics and antecedents, meaning how you live your life. You keep eating tuna fish, then you likely have mercury toxicity.

00:02:25:23 – 00:02:51:21
Dr. Tom Obryan
That’s an antecedent. So genetics and antecedents determine where the weak link in is in the chain. You keep pulling down the chain, it’s going to break. Well, what’s the pull on the chain? That’s the root cause. The pull on the chain is inflammation always. And the more time that you put into addressing where is my first? Do I have inflammation?

00:02:51:21 – 00:03:19:09
Dr. Tom Obryan
Because most people don’t have a clue that they’ve got this inflammatory state going on. Do I have inflammation? And then if yes, you find out you have, why do I have inflammation? And that is the million dollar question. Yes, inflammation is just the activation of your immune system. And Ms. Mrs. Patient, your immune system is the armed forces in your body there to protect you.

00:03:20:01 – 00:03:42:05
Dr. Tom Obryan
There is an army and Navy and Air Force, the Marines, a Coast Guard, we call them a big ig m cytokines. There are different branches of the immune system, different branches of your armed forces there to protect you. So the million dollar question is what is it trying to protect you from because the inflammation is pulling on the chain?

00:03:42:05 – 00:03:55:07
Dr. Tom Obryan
Well, why is your immune system activated? That’s the root mechanism behind all chronic diseases is investigating where is the inflammation coming from?

00:03:56:12 – 00:04:36:10
Nathan Crane
Yeah. And for people who don’t realize, you know, not all infamy, not all inflammation is bad, right? You have acute inflammation, which is, you know, as you mentioned, an injury. For example, you sprain your anchor ankle, whatever. It’s like your body is sending inflammatory cytokines to that area to swell it up, to heal that tissue. But in my research with cancer for the past decade plus when we’re looking at chronic inflammation, so just so people don’t get confused, acute inflammation or inflammation too, you know, attack a virus or bacteria infection or whatever is good for you is your body’s defense is just, as you said, chronic inflammation where it’s low grade is continuously happening, 24

00:04:36:10 – 00:05:02:22
Nathan Crane
seven. That is actually one of the core causes of cancer. And as you said, one of the underlying mechanisms of all chronic diseases, autoimmune disease, neurodegenerative disease, etc., diabetes, every single one of these chronic diseases has an inflammatory component to it. What’s unique about cancer, specifically that I’ve discovered is a cancer that chronic inflammation is one of the core causes of cancer.

00:05:02:22 – 00:05:32:07
Nathan Crane
So what causes inflammation? I want to ask you that next. And I think that’s where you’re going. But number two, like for cancer, the process of having chronic inflammation actually damages the cells integrity and can actually cause cancer because that chronic chronic inflammatory state words where it’s degradation, repair, degradation, repair, degradation, repair, the process of that actually causes cancer, which is something we want to avoid, obviously.

00:05:32:07 – 00:05:38:14
Nathan Crane
So back to that question. As you know, what is at the root cause of chronic inflammation.

00:05:40:02 – 00:06:05:19
Dr. Tom Obryan
When you’re absolutely right, if we didn’t have an active immune system protecting us, we wouldn’t live one day on the planet. And that’s not an exaggeration. We’re constantly being assaulted by things that can be damaging to us in what we breathe and what we eat and the water we drink. So inflammation is not bad for you. It saves your life every single day.

00:06:06:12 – 00:06:36:20
Dr. Tom Obryan
Excessive inflammation is bad for you. And that’s the million dollar question. You know, I just had the privilege last week of interviewing Fran Drescher, the nanny. And, you know, Fran founded Cancer Schmancer. She’s a 23 year survivor of uterine cancer. And she asked the question, why did I get cancer? And she was very grateful to her oncologist. She still sees that oncologist.

00:06:36:20 – 00:06:57:24
Dr. Tom Obryan
She was telling me this become a friend and she saved her life. Fran feels that way. She saved my life, but she couldn’t answer any of the questions that I had about why did I get cancer. So Fran did a deep dove and found it, wrote the book Cancer Schmancer, and then founded the organization to educate people on all of this.

00:06:58:16 – 00:07:25:22
Dr. Tom Obryan
And that’s the million dollar question. What is it that’s activating the immune system to produce this excess of inflammation? And there is no root cause to that. There are many causes. It can easily be food sensitivities. You’re eating a food, but if it doesn’t make you sick, if you don’t feel bad when you eat the food, you think it’s okay for you?

00:07:25:22 – 00:07:48:21
Dr. Tom Obryan
Well, no, it’s not. You know, it may be activating your immune system and we know, for example, with wheat as a model for every one person that gets gut symptoms with wheat, there are eight. Then don’t they feel fine when they eat? We eat, they get brain symptoms, brain fog or seizures, they get joint symptoms or skin cells.

00:07:48:21 – 00:08:15:00
Dr. Tom Obryan
And listen to this one in the journal Gastroenterology, they looked at children with drug resistant epilepsy, which means that they’ve been on at least three medications that don’t work to qualify for the diagnosis of drug resistant epilepsy, 50% of children with drug resistant epilepsy go into complete remission on a gluten free diet.

00:08:15:20 – 00:08:30:18
Nathan Crane
50% 75% of children with drug resistant epilepsy. So so they have full blown epilepsy. They go into seizures and, you know, basically epilepsy in full bloom.

00:08:30:18 – 00:08:37:14
Dr. Tom Obryan
That’s right. You don’t get that that diagnosis unless they’ve tried three epileptic drugs that don’t work.

00:08:37:14 – 00:08:43:06
Nathan Crane
Wow. And 50, 50% of it get completely healed or go into remission. When they get.

00:08:43:09 – 00:08:50:07
Dr. Tom Obryan
Leg, they go into remission. Not not healing. You don’t heal from that kind of stuff. You put it into remission.

00:08:50:15 – 00:09:08:00
Nathan Crane
Yeah, right. I have a buddy. I had him on the podcast. He, you know, has been epileptic and he cleaned up his diet, got alcohol, you know, etc. cetera, exercise, meditate, all these things. And he has been he hasn’t had a symptom of epilepsy for 13 years, I think I think is correct.

00:09:08:00 – 00:09:32:20
Dr. Tom Obryan
Exactly. He stopped pulling on the chain. Yeah. Because the weak link for him was his brain, which means that gluten for these children was pulling on their chain. Now, why don’t our neurologists know this? Because this published in the Gastroenterology Journal, and neurologists don’t read gastroenterology journals. They read neurology journals. You know, salt foods are.

00:09:33:09 – 00:09:44:21
Nathan Crane
Should realize that neurology and gastroenterology are deeply and intimately directly connected, which, you know, more scientists and doctors are learning this today. Right.

00:09:44:21 – 00:09:47:13
Dr. Tom Obryan
That yeah. The gut brain connection. Yeah, that’s our gut.

00:09:47:13 – 00:09:50:18
Nathan Crane
But most people don’t know that is what you’re saying. Right.

00:09:51:06 – 00:09:56:15
Dr. Tom Obryan
Right. And and that’s your job. And my job is to educate them on that. Yeah.

00:09:57:15 – 00:10:21:05
Nathan Crane
Why can people go to Europe. I mean, I’ve heard this anecdotally, so I can’t say it’s, you know, guaranteed, but I have literally heard it from so many people who have gluten sensitivities and they’re aware of gluten sensitivities and here in the U.S. and then they go to Europe, they go to Italy, for example. They wheat the whole time they’re there, pasta, bread, and they said they have no reactions at all.

00:10:21:13 – 00:10:24:05
Nathan Crane
They come back here, they can have any gluten. Why is that?

00:10:24:21 – 00:11:08:04
Dr. Tom Obryan
Yeah. Yeah, that’s a really good question. And that’s it’s it’s an easy answer once you know the science that the reaction to the proteins of wheat that the that activate the immune system and cause inflammation. It’s the proteins of wheat gluten and other proteins that activate the immune system. It doesn’t activate the gut or bloating and gas and constipation and diarrhea very often it’s the fodmaps in wheat, the fermentable carbohydrates that activate the bloating and the gas, which means the symptoms.

00:11:08:04 – 00:11:28:13
Dr. Tom Obryan
Oh, I don’t feel so good when I get all bloated and blah blah blah. And Doc, I can go to Europe and I can eat the wheat. Well, that’s. There’s only one reason why. That’s because the wheat in Europe is lower in Fodmaps. So you don’t get the gut symptoms, but you still activate the immune response. So it’s the weak link in your chain is your brain.

00:11:28:13 – 00:11:32:01
Dr. Tom Obryan
When you come home, you’re more vulnerable to getting seizures again.

00:11:32:19 – 00:11:42:13
Nathan Crane
Really? So are you saying there’s not any safe wheat to eat on the planet today?

00:11:42:13 – 00:12:17:09
Dr. Tom Obryan
I guess the way I would answer that question is that Maureen Leonard at Harvard, a famous gastroenterologist, she’d research that subject, and she looked at over 60 papers, published papers on that topic. And she said that gluten activates transient intestinal permeability, the leaky gut in all humans who consume it. Without exception, everyone has. Two things happen when they eat wheat.

00:12:18:01 – 00:12:46:04
Dr. Tom Obryan
One, they activate leaky gut. Leaky gut means that the cells open up a little bit inside your gut. So water comes from the body into the lumen of the gut. And it’s a safety mechanism to wash out the toxin that it’s just identified. That’s what leaky gut this for. And it does the second thing it activates the major amplifier of inflammation called NF Kappa B in the gut to kill this threat.

00:12:47:03 – 00:13:18:15
Dr. Tom Obryan
And Alessio Fasano at Harvard has published a number of papers that talk about this. Gluten is misinterpreted as a harmful component of a bug that the protein structure of wheat looks like the outer shell of a microorganism, a bug. So your immune system, when you eat this thing wheat, you have the same body as your ancestor thousands of years ago, same kidney, same liver, same immune system.

00:13:19:02 – 00:13:45:00
Dr. Tom Obryan
We use our brains more. So we’ve got creature comforts and more food available, but we have the same body in our ancestors before agriculture. We’re nomads. They followed the herds. And so their first priority was always food. So they’re walking around, they see something, they pick it up. First they smell it, then they nibble it, then they eat it.

00:13:45:17 – 00:14:13:16
Dr. Tom Obryan
And if it had bad bugs that they couldn’t identify by and they ate it right inside the first part of the small intestine, we have centuries standing guard. I think of the soldiers at Buckingham Palace with those big hats. You know, they’re as dormant as can be. There’s still a fence still, and they don’t move. And in our guts, we’ve got the sentry standing guard called toll like receptors.

00:14:14:14 – 00:14:38:13
Dr. Tom Obryan
And they’re right inside. They’re all over the body. But right inside the first part of the small intestine. And they’re watching everything that’s coming out of the stomach into the first part of the small intestine. And if they see any threat, what’s so whatever they activate intestinal permeability, the proteins on you learn to increase permeability to wash it out.

00:14:38:19 – 00:15:03:09
Dr. Tom Obryan
More water comes into the gut to wash it out with the poop and they activate nf kappa B That’s the job of toll like receptors in the first part of our small intestine. And it was Fasano that explained to us in 1997 this mechanism. And he says, I mean, in the papers you see it in the science gluten is misinterpreted as a harmful component of a bug.

00:15:03:18 – 00:15:06:02
Nathan Crane
Misinterpreted by our immune system as what?

00:15:06:11 – 00:15:35:02
Dr. Tom Obryan
By our immune system because it the amino acid structure of these indigestible parts of wheat, the proteins that no human can digest, the amino acid structure of those pieces of wheat look like the amino acid structure of the outside of a bug. And so your immune system gets activated in every human when you’re exposed to gluten.

00:15:35:14 – 00:15:38:03
Nathan Crane
So why do some people have symptoms and others don’t?

00:15:39:18 – 00:16:07:16
Dr. Tom Obryan
Because well, the symptoms are you mean gut symptoms from fodmaps? My gosh, if you talked about symptoms in general, just Google gluten and schizophrenia here come the studies how sometimes it works. Yeah, it puts it in remission. And this is from psychiatrists and psychiatry journals. They do an OMG. Oh my God, look at this. One year in a gluten free diet and the patients off all medications and stable.

00:16:08:00 – 00:16:32:04
Dr. Tom Obryan
And you see those kinds of case studies again and it just Google gluten and rheumatoid arthritis. Yehuda Schonfeld is the godfather of autoimmunity. And what I mean by that is that in his immunology department at Tel Aviv University, there are many, many Doric docs who have gone back to get their Ph.D. in immunology, 26 of them. There are many more.

00:16:32:15 – 00:17:13:05
Dr. Tom Obryan
But when I interviewed Schonfeld, 26 of them Chair Departments of Immunology in Med Schools and Hospitals around the world. They’re his students. This is The Godfather. He published a paper in March of 2022 and the paper, the title of the paper was The Effects of a Gluten Free Diet on Non-Celiac Autoimmune Disease. And he did a literature search and he showed that 79% of the patients get better on autoimmune patients, get better on a gluten free diet.

00:17:13:11 – 00:17:48:03
Dr. Tom Obryan
And this was confirmed in 65% of the studies. Not every patient, not every time, 79% of the patients, 79.5%, to be exact, get better on a gluten free diet. And then he showed the autoimmune diseases that he did research. There were 28 different auto immune diseases. The most common that responds is Hashimoto’s thyroid disease and it’s 87% of Hashimoto’s patients get better on a gluten free diet.

00:17:48:17 – 00:18:30:03
Dr. Tom Obryan
The next most common one was psoriasis and the third most common one was inflammatory bowel disease. And once again, these are not celiac patients, these are other autoimmune diseases. And then he had pancreatitis, autoimmune pancreatitis, autoimmune myocarditis, rheumatoid arthritis, most inflammatory bowel disease list went on and on and on. 28 different autoimmune diseases that get better on a gluten free diet because every human has this inflammatory mechanism that occurs and this leaky gut that occurs when they’re exposed to wheat, every human.

00:18:30:12 – 00:18:58:05
Dr. Tom Obryan
And when you look at the development of autoimmune diseases, there is a perfect storm in the development of autoimmune diseases which is centered around leaky gut. So when you get leaky gut, you become extremely vulnerable to developing an autoimmune condition dependent on where the weak link in your chain is.

00:18:58:05 – 00:19:33:06
Nathan Crane
I want to get into what leaky gut is and why that why that happens. I understand a little bit about the mechanisms of it, but I’d love for you to talk about that. But I want to stay on gluten specifically for a moment, because do you think. Well, okay, first of all, those studies that were referenced where he saw, you know, significant improvement in 28 different autoimmune diseases, 79% of people getting better by going on a gluten free diet, which is massive, is incredible because we know that massive there’s at least 100 autoimmune diseases we know of.

00:19:33:12 – 00:19:58:19
Nathan Crane
And if you actually group, it’s not grouped in the data like cancer. All cancers are grouped under cancer. You know, all diabetes, you have like four or five forms of diabetes. Now they’re all basically well, not not neurodegenerative diabetes, but diabetes. Heart disease with all the autoimmune diseases aren’t technically grouped under one disease profile right now in the data of diagnoses in death.

00:19:58:19 – 00:20:05:10
Nathan Crane
But if you did, what I’ve seen is actually that would be the number one killer above cancer and heart disease. Is that right?

00:20:05:13 – 00:20:06:17
Dr. Tom Obryan
That’s right. That’s right.

00:20:06:17 – 00:20:29:16
Nathan Crane
So that’s that’s that’s unbelievable to think about. And knowing that the mechanism for these autoimmune diseases seem to be pretty much the same. And we can talk about I’d love for you to talk about nuances about that. And maybe the solutions are actually very similar, but were those studies asked? These were these were the randomized controlled trials. Where was this?

00:20:29:16 – 00:20:53:16
Dr. Tom Obryan
Oh, there’s hundreds of there’s hundreds, hundreds. There’s not like three or four. What type of study does every type of study on this when when when you look at these, you say what? What? And you just keep going deeper and deeper into it. And it becomes, how can you not recognize this? Well, you know, there’s no evidence. Don’t.

00:20:53:17 – 00:21:26:06
Dr. Tom Obryan
Excuse me. You mean you haven’t read the evidence? Know. So, Alessio Fasano, professor of medicine, Harvard Medical School, professor of nutrition, Harvard School of Public Health, chief pediatric gastroenterology at Mass, General at Harvard. The director Celiac Research Center at Harvard. The Director of Mucosal Immunology at Harvard. This guy’s got five titles. Any one title is a lifelong goal for someone at the top of their game.

00:21:27:04 – 00:21:54:18
Dr. Tom Obryan
He’s got five. We think he’s going to win the Nobel Prize. We really, truly do, because it was him and his team in 1997 that identified the mechanism by which this thing we now know as leaky gut occurs the production of the proteins only alone, and it opens up the junctions to have water come into the gut, to wash out cholera, wash out the toxin that the person’s been exposed to.

00:21:55:02 – 00:22:19:04
Dr. Tom Obryan
That’s how it occurs is by this protein solubility increasing? I use the analogy of shoelaces, so like your cells in your gut are connected together by shoelaces. And when you have a high school kid that’s not tying his shoes, his shoes flop on his feet. That’s a leaky gut. That’s when the shoe laces are untied. And it’s the protein Zombieland that unties the shoe laces.

00:22:20:06 – 00:22:27:20
Dr. Tom Obryan
So why does that happen? What happens? Because you need more water in the gut to wash out the threat, whatever the threat is.

00:22:28:04 – 00:22:34:02
Nathan Crane
So it’s so that’s a normal biological safety defense mechanism. Leaky gut by itself.

00:22:34:02 – 00:23:05:19
Dr. Tom Obryan
Exactly, exactly. Exactly. It’s normal. It’s life saving. Those ancestors that did not have a good functioning toll like receptor system in their gut, they died and they didn’t reproduce. Their lineage died off those that had good defense mechanisms to protect themselves against toxins in the food that they may have been exposed to in their scavenging for food. As hunter gatherers, they lived and they reproduce and they develop that that defense mechanism to protect themselves.

00:23:06:01 – 00:23:07:23
Dr. Tom Obryan
We all inherited that.

00:23:08:04 – 00:23:19:10
Nathan Crane
So if someone says we have if someone says, I have leaky gut, that’s not really the context. That’s not really like an accurate thing to say. Right? Right.

00:23:19:14 – 00:23:21:10
Dr. Tom Obryan
What what when you go.

00:23:21:15 – 00:23:22:04
Nathan Crane
Yeah, go ahead.

00:23:22:22 – 00:23:25:21
Dr. Tom Obryan
What’s actor says? I have excessive, leaky gut.

00:23:25:22 – 00:23:28:02
Nathan Crane
Everybody’s got inflammation. Gotcha.

00:23:28:05 – 00:23:55:16
Dr. Tom Obryan
Yes. Yeah. So Fasano and his team, he is so careful of what he says always so that it is not misquoted because he’s out there. You know, he he’s charged, you know, he’s got five different titles at Harvard when you see and he’s going to add hundreds of papers to his name. Research papers. I think it’s about 400 now.

00:23:55:16 – 00:24:24:01
Dr. Tom Obryan
I’m not sure I stopped counting a few years ago. You’ll see eight authors on a research paper. And the last one, Alessio Fasano, he put his stamp on it. Right. This paper he wrote himself, that’s rare all by himself, meaning he really wanted to get this message out. So if you if you grant this guy that all right, he’s one of the leaders in the field.

00:24:24:01 – 00:24:53:17
Dr. Tom Obryan
Okay. And he’s got a number of titles at a very prestigious research university in the world. Okay. So what’s his message? The title of the paper, All Disease, begins in the, quote, Leaky gut, the role of the protein zone in the development of chronic inflammatory diseases. Now, remember, I said at the beginning, 14 of the 15 top causes of death are chronic inflammatory diseases.

00:24:54:12 – 00:25:28:13
Dr. Tom Obryan
And here we have this guy, this top of the world researcher here with so many credentials telling us all disease begins in the leaky gut. When you read that paper, it changes your paradigm because he talks about the perfect storm in the development of chronic inflammatory diseases. There are five factors in the perfect storm versus genetics. Not much you can do about the genes that you’ve been given that, yeah, that’s a deck of cards.

00:25:28:13 – 00:26:00:06
Dr. Tom Obryan
You got, but there’s a whole lot you can do with those genes. Now, some doctors say, Well, we’re going to turn that gene often. You can’t turn genes off. Genes operate on dimmer switches, and you certainly can dim down the expression of a gene or turn up the expression of the gene. And for a younger, more vital life, you want to turn up the genes of anti inflammation and regeneration and turn down the genes of inflammation and tissue destruction.

00:26:00:07 – 00:26:02:01
Dr. Tom Obryan
You know, that’s that’s a rational goal.

00:26:02:07 – 00:26:15:24
Nathan Crane
Yeah. But the first it’s more accurate to say the expression of those genes. Right. Like you said exactly. You can turn them up. You can turn them down. You can’t completely turn the genes. Don’t just go away. They don’t just disappear. You still.

00:26:15:24 – 00:26:17:00
Dr. Tom Obryan
Have. Exactly right.

00:26:17:00 – 00:26:24:04
Nathan Crane
Just not expressing into, you know, multiple, you know, replicating into, you know, the DNA of those genes.

00:26:24:04 – 00:26:45:22
Dr. Tom Obryan
Yeah. Look, if you’ve got the APOE4 gene for Alzheimer’s and you’ve had two family members that have died of dementia, you know, you’d be pretty scared. But it’s a wake up call. And any time my patients have apology for, I sit down with them and say, you know what? I have to read to you from the book. And they look at me and I say, The book of life.

00:26:46:11 – 00:27:14:08
Dr. Tom Obryan
You need to understand the weak link in your chain is your brain. That’s the weak link in the chain. Can’t do anything about that. But we certainly can do a lot as to how much you pull that chain because the weak link is going to break. That’s one of your weak links. Patients understand that. And so how do we not pull on the chain, reduce inflammation, reduce the pull on the chain?

00:27:15:14 – 00:27:35:13
Dr. Tom Obryan
And I have so many patients that we’ve done their tests. You know, we we do follow up test first. When we do our first test, they’re a mess. You know, they’ve got lots of it. I mean, the tests that I’d recommend everyone do because they’ll shock the hell out of you is the neural zoomer. Plus it’s a blood test in the laboratory is vibrant wellness.

00:27:35:13 – 00:28:03:08
Dr. Tom Obryan
I have no association with them, but it is the best test in the world. It identifies 53 markers of inflammation in your brain, and it’s shocking. Nathan Yeah. I mean, if your audience listens to what I’m about to tell you, Blue Cross Blue Shield, published in February of 2020, they said, We’ve got a real problem here, but no one paid attention to it because that’s when the virus came out.

00:28:03:23 – 00:28:35:20
Dr. Tom Obryan
And so everyone was caught thinking about the virus. Right. But they said, we’ve got a real problem here. And the previous four year period, there was a 407% increase in the diagnosis of Alzheimer’s in four years in 30 to 44 year olds. Well, it’s like wake up, world, wake up. You see that neuro zoomer plus? And as I said, it’ll shock the hell out of you.

00:28:36:02 – 00:28:37:02
Nathan Crane
Same thing that happened with.

00:28:37:04 – 00:28:38:19
Dr. Tom Obryan
Cancer brain is right now.

00:28:39:03 – 00:28:44:05
Nathan Crane
Yeah, I’m going to do that test, by the way. Thank you for sharing that. The because I’m curious.

00:28:44:20 – 00:28:51:03
Dr. Tom Obryan
Excuse me when when when you do that test, I will come on and we’ll interpret it online.

00:28:51:10 – 00:28:51:18
Nathan Crane
Okay.

00:28:52:02 – 00:28:59:19
Dr. Tom Obryan
So that so the people on your show, so that people can follow along and if they want, they they should do the test also.

00:29:00:03 – 00:29:25:05
Nathan Crane
Okay, that’s very cool. Thank you for that. Thank you for offering that. Yeah, it’s the same thing with cancer that we’ve seen. You know, young people think, oh, I don’t know if I worry about cancer. It doesn’t run in my family. I’m 30. I don’t have to worry about it. A recent study just came out looking at a 79% increase in cancer diagnoses in young people under 50.

00:29:25:05 – 00:29:25:14
Dr. Tom Obryan
Years.

00:29:26:01 – 00:30:01:18
Nathan Crane
In the last 30 years alone. So, you know, this this modernized diet and lifestyle, this this mechanistic civilization, this extreme exposure to manmade toxic chemicals, you know, the excessive stress, all the things we can talk about that actually cause chronic inflammation, the damage, the mitochondria that are leading to these chronic diseases. It is exceeding all understanding of of, you know, young people being diagnosed with chronic diseases at higher rates and younger than ever before than anyone ever thought.

00:30:01:24 – 00:30:12:17
Nathan Crane
And it’s very and these things are primarily preventable, as we know, but don’t know about it. And you just keep doing the same old things. Guess what’s going to happen? Unfortunately.

00:30:13:08 – 00:30:44:02
Dr. Tom Obryan
Yeah. Yeah, exactly right. A paper came out six weeks ago. They have new technology to identify plastic in bottles of water. And we’ve heard about the dangers of microplastics, but now they have laser technology to identify. Nanoplastics, which are billionth of a gram, is a nanoparticle of plastic and in three different brands of water, they looked at one liter bottles of water, in plastic bottles in three different brands.

00:30:44:02 – 00:31:14:05
Dr. Tom Obryan
The average was 240,000 nanoparticles of plastic shoes and that stuff. When you drink it, it goes right through into your bloodstream and it goes right through the blood brain barrier into your brain. It accumulates in your brain and it activates the immune system in your brain to fight this toxin that’s in there. And you do the neural zoomer plus, and you come back and you’ve got 25 of the 53 markers elevated in your brain.

00:31:14:05 – 00:31:40:02
Dr. Tom Obryan
And by definition, when you have elevated antibodies, you’re killing off more cells in your making. So it’s no surprise that there’s a 407% increase in the diagnosis of Alzheimer’s in 30 to 44 year olds, because people don’t recognize how toxic our world is. They don’t want to hear that their favorite tutti frutti lipstick is full of so much crap that accumulates in your body.

00:31:40:02 – 00:31:46:04
Dr. Tom Obryan
Excuse me, you know, but it’s Wake Up World. All right, back to Fasano.

00:31:46:11 – 00:31:54:12
Nathan Crane
Well, on that point, before we go back to Fasano, I want to say, because you just mentioned water, that’s why I drink and recommend stainless steel or glass.

00:31:54:12 – 00:31:55:05
Dr. Tom Obryan
Absolutely.

00:31:55:05 – 00:32:28:14
Nathan Crane
Stainless steel or glass. We know stainless steel doesn’t leach heavy metals. Aluminum does leach heavy metals in your liquids. There’s actually the Stanley large cups that are now the big fad my daughter go in the other day by the way, was how I learned about this stainless steel. Okay, the bottom of if you look at the bottom and it has a little cap on it, that cap actually is made with lead and over time, that cap on the inside wears down and leaches lead into your water.

00:32:28:14 – 00:32:52:06
Nathan Crane
She think you’re drinking stainless steel water, right? Not leaching heavy metals. And yet these many, many bottles have been tested and filled with lead. So even stainless steel, you got to really look out for what you’re getting or just go glass. But, you know, these these ones have been tested significantly. The hydro flasks, there’s no cap in the bottom.

00:32:52:06 – 00:33:11:15
Nathan Crane
It’s a dimple. And so, you know, these don’t leach. But simple things we can do, right? Filter your water, filter your air, drink from stainless steel, drink from glass. You’re still going to be exposed to toxins. But we can mitigate we can reduce our risk significantly. And I just want to say that I also wanna say one other thing about the brain, the neurotoxins in the brains.

00:33:11:15 – 00:33:41:07
Nathan Crane
I think this is important. You have all these neurotoxins collecting in the brain, causing chronic inflammation. What a lot of people don’t realize, the only way to drain to remove these toxins from your brain is to activate your lymphatic system. My right. And the only way to activate that or to fully, fully release the toxins from your brain, where they leave the lymphatic system from your brain and get dumped into the rest of your lymphatic system in your body is to get adequate sleep.

00:33:41:16 – 00:34:04:10
Nathan Crane
It’s turned down when we’re awake and it’s turned all the way up when we’re sleeping. But the research I’ve done, you correct me if I’m wrong, it on average it takes about 8 hours of sleep to do a full lymphatic drain of the brain. And how many people are actually sleeping? 8 hours. How many people are not getting as many of those toxins out of their brain as they could be?

00:34:05:14 – 00:34:33:14
Dr. Tom Obryan
Well, you bring up a really good point, and that sleep is critically important. It’s one of the primaries in the development of low grade inflammation. There are other ways to drain lymphatics, but that’s the primary. And number one most important is getting adequate sleep. And you are right, the lymphatics only drain. When we are in a parasympathetic dominant state where we are, our bodies are relax.

00:34:33:14 – 00:34:53:01
Dr. Tom Obryan
It’s like the 10th day of a two week vacation with no kids. You know that when you’re in that frame of mind, when you’re in that frame of mind and the biggest the, biggest decision of the day is, is lunch at the pool or at the beach right. That doesn’t happen very often.

00:34:53:01 – 00:34:57:19
Nathan Crane
So I’m actually missing my kids right now has been ten days. But this is have it all. Enjoy it.

00:34:58:16 – 00:35:24:16
Dr. Tom Obryan
Yes. Right, right, right. That’s a parasympathetic dominant state. And for most of us, the only time we get there is when we’re in a good, deep sleep mode. So that’s one reason why. But if you were someone that meditates, I have a friend that’s been well, my friend Jeffrey Smith, who founded the Institute for Responsible Technology, really brought to our attention in the world about the dangers of glyphosate.

00:35:25:08 – 00:36:04:11
Dr. Tom Obryan
Jeffrey has meditated every day or something like 34 years now, something like that. And so, you know, people can develop that tool of getting into a parasympathetic dominant state when you’re awake. But that’s why one reason why it’s so critically important to get quality sleep is that you only heal when you’re in that parasympathetic dominant state. When your heart rates relax, your breathing is slow and deeper and that it’s it’s the only time we heal and draining the brain, activating the lymphatics is a major part of that.

00:36:05:22 – 00:36:39:21
Dr. Tom Obryan
Okay, so Fasano is perfect storm number one is genetics. Number two of the five factors in the perfect storm is environmental triggers that activate our genes. And it’s your environment that has its fingers on the knob of the dimmer switch of your genes, turning your genes up, turning your genes down. It’s your environment that means the outdoor environment and also the indoor environment.

00:36:39:21 – 00:37:12:04
Dr. Tom Obryan
Put all of the accumulated toxins that you may have. Or do you have enough of the right enzymes? Do you have enough of the right hormones? The internal environment and the external environment have their fingers on the dial of your genetics. Okay, that’s number two. And given the lives that we live, most of us, I venture to say all of us have way too many of the wrong things.

00:37:12:04 – 00:37:35:12
Dr. Tom Obryan
The most common source of environmental triggers is what’s on the end of your fork, what you put in your mouth. And for most of us, we are out of balance in our gut between the good guys and the bad guys. Now, that’s called dysbiosis. That’s the geek term for it, but it means too many bad guys and not enough good guys.

00:37:36:08 – 00:37:59:02
Dr. Tom Obryan
And when you have too many bad guys in your gut, you have an inflammatory state in your gut. The 75 to 80% of the immune systems in your gut, because that’s where the most threat is. So that’s where most of the army needs to be to protect you before our ancestors walking around, looking for food, picking stuff up and sniffing it, nibbling and then eating it.

00:38:00:02 – 00:38:24:05
Dr. Tom Obryan
75 to 80% of immune systems. In your gut. So it gets activated to protect you from all of the garbage that you’ve put down there over the years. It gets activated to protect you. So you get this inflammation in your gut from the too many bad guys, not enough good guys. And the inflammation in the gut creates number four.

00:38:24:17 – 00:38:56:16
Dr. Tom Obryan
So what’s number four, Mrs. Patient? Your digestive system is a two. It starts at your mouth with saliva, and that’s why you have to chew. And it goes all the way to the other end. One big long 220 to 25 feet long, the inside of the tube is lined with cheesecloth. So when you swallow a bite of a hamburger and you chew it three or four times and gulp it, as opposed to chewing it 15, 20 times like we should, but we gulp it down.

00:38:56:16 – 00:39:19:11
Dr. Tom Obryan
You’ve got these big clumps of meat in there. That stuff can’t into your bloodstream. It’s got to be broken down, smaller and smaller and smaller. That’s what digestion is. It’s the enzymes. So if you think of protein like a pearl necklace, the acid in your stomach and there’s the clasp of the pearl necklace, now you have a string of pearls.

00:39:19:11 – 00:39:43:05
Dr. Tom Obryan
They’re called amino acids. They’re all put together to make protein. And our enzymes act as scissors to cut that pearl necklace smaller and smaller. Snip snip snip snip snip. Until you’re down to each pearl of the pearl necklace which goes right through the cheesecloth into the bloodstream. That’s absorption. And when it gets in the bloodstream, your bloodstream just a high way.

00:39:43:15 – 00:40:09:01
Dr. Tom Obryan
There it goes on the highway. Everything is going in the same direction, but everything’s bouncing into each other, you know. But now you’ve got these raw materials, these amino acids that you’re called the building blocks of muscle cell and bone cell and brain cell. But they’ve got in they went through the cheesecloth into the bloodstream. Now your body can use them to make new bone cells and brain cells and organ cells.

00:40:09:01 – 00:40:45:21
Dr. Tom Obryan
When you have dysbiosis, too many bad guys, not enough good guys in the gut creating this inflammatory state, the inflammation tears, the cheesecloth. Now you’ve got tears in the cheesecloth. So bigger clumps of the food that you’re eating can get through the torn cheesecloth into the bloodstream before it’s been broken down, small enough, those bigger clumps are called macromolecules, and these macromolecules get in the bloodstream.

00:40:46:06 – 00:41:13:23
Dr. Tom Obryan
There they go. They’re in the bloodstream now. That’s number four. Leaky gut is the tares in the cheesecloth. Now, you’ve got at these tears. In the end, it doesn’t matter if it’s chicken or raspberry or whatever it is. If these macromolecules get through into the bloodstream now your immune system says, Whoa, what’s that in the bloodstream? That’s not something I can use to make new bone cells or brain cells.

00:41:13:23 – 00:41:27:12
Dr. Tom Obryan
I better fight that. Now, you make antibodies to chicken or to beef or to raspberry or to tomato. It doesn’t matter. That’s number five. Chronic systemic inflammation.

00:41:27:12 – 00:41:28:15
Nathan Crane
And now you have food.

00:41:28:16 – 00:41:29:16
Dr. Tom Obryan
Pulling on the chain.

00:41:29:24 – 00:41:34:22
Nathan Crane
Now you have a food sensor that’s right to those foods. It’s not those or those kinds of infection.

00:41:35:23 – 00:41:55:20
Dr. Tom Obryan
Don’t you know? Or you have a chronic yeast infection in your gut or you got a mold infection in your gut, or you’ve got artificial sweeteners that they kill the good guys or you’re exposed to glyphosate from eating conventional foods. They kill the good guys in the gut and create all this inflammation that there is a cheesecloth. I mean, there’s a lot to learn of what to do.

00:41:55:20 – 00:41:57:09
Dr. Tom Obryan
But the goal is.

00:41:57:09 – 00:41:58:01
Nathan Crane
Heavy metal.

00:41:58:04 – 00:42:27:09
Dr. Tom Obryan
Recognize all disease begins in the leaky gut and that pull on the chain that manifests your genetic and antecedent determined weak link is that pull on the chain is the chronic systemic inflammation that comes from the gut. So that’s the Santo’s message. All disease begins in the leaky. This is Ph.D. material. You can’t get it in one hour.

00:42:27:19 – 00:42:30:12
Dr. Tom Obryan
Hopefully you’ll you’ll listen to this again and again.

00:42:30:24 – 00:42:52:00
Nathan Crane
I think I think I mean, this is modern science backed up significantly by extensive amounts of research. But I think hypocrisy says the same thing. 2000 years ago. Right. Basically, like all disease begins in the gut. And so, you know, he exactly right. He had theory and his own personal anecdotal evidence. But now it’s it’s very backed up by hard science.

00:42:52:00 – 00:43:13:07
Nathan Crane
And and I believe it. And as you said, when people clean up the culprits that are causing the excessive leaky gut, they’re causing the tares in the intestinal lining is creating that intestinal permeability once that gets cleaned up and healed because it’s very possible to clean that up and heal it because intestine cells replicate every watt 24 hours.

00:43:13:18 – 00:43:15:21
Nathan Crane
Right. So 24, 48 hours.

00:43:15:21 – 00:43:17:21
Dr. Tom Obryan
Three, three, 3 to 5 days.

00:43:17:21 – 00:43:19:21
Nathan Crane
3 to 5 days, very fast.

00:43:19:21 – 00:43:21:19
Dr. Tom Obryan
It’s the intestine you’re talking about. Yeah, very.

00:43:21:19 – 00:43:43:17
Nathan Crane
Yes. Yeah. It depends what part it has. And so it’s you can, you know, heal it up and clean it up, but not if you keep putting in the same the same components that are damaging the intestinal lining, which, as you said, you know, chronic inflammation is doing it to me, bad guys, not enough good guys in terms of bacteria, fungus, but also heavy metals.

00:43:43:23 – 00:43:54:20
Nathan Crane
Tear up the intestinal lining. Right. Chronic stress that causes that chronic inflammation and can tear up the intestinal lining, is that right? There’s a number of factors that are that are contributing towards it.

00:43:54:20 – 00:44:03:00
Dr. Tom Obryan
Yes, exactly. Exactly. The goal becomes to understand how do I build a healthy, diverse microbiome?

00:44:03:15 – 00:44:25:10
Nathan Crane
Really quick before we get to that, I want and I’d love for you to talk a little bit about that if you can if you if you have some time. But before on the wheat question, is it gluten in all foods? Rye, barley, wheat, einkorn, kamut? Is it all forms of gluten or is it specific forms of gluten.

00:44:26:10 – 00:45:01:08
Dr. Tom Obryan
That question gluten, gluten gluten is a category of foods. There’s gluten in rice. There’s gluten in corn and wheat and rye in barley. But the family of gluten proteins that includes wheat, rye and barley, those are the ones that no human can digest. Those are the ones that activate. They activate toll like receptor four in the proximal part of the small intestine.

00:45:01:08 – 00:45:21:17
Nathan Crane
Wow. So, I mean, if anyone walks away from this and goes, man, I should keep eating wheat, you miss the message. You know, rewind it and listen to this again, because the number one takeaway here is, you know, any gluten from wheat? Ryan Barley, including.

00:45:21:17 – 00:45:22:03
Dr. Tom Obryan
Until.

00:45:22:08 – 00:45:23:07
Nathan Crane
Say ten until.

00:45:24:17 – 00:45:26:09
Dr. Tom Obryan
Yeah, yeah, you’re right. I mean.

00:45:26:09 – 00:45:27:23
Nathan Crane
We should we should avoid it completely.

00:45:28:20 – 00:45:51:00
Dr. Tom Obryan
Until a person gets sick enough and they’ve tried enough other things that work a little bit but don’t work really well until they’re sick enough. Many people won’t pay attention to this. And once they do and they feel like a million bucks in a shorter period of time, you know, they just feel so much better and they say, well, I’m going to go buy and try again.

00:45:51:07 – 00:46:11:18
Dr. Tom Obryan
And it always makes my day when I see a patient who said, Doc, I went back and I tried some pizza. You know, I was feeling great, but I, you know, I had some pizza. Oh, my God, I feel terrible. The next day, all of my sipped I said, great. Oh, great. Congratulations. And now nobody can argue with you.

00:46:11:19 – 00:46:19:07
Dr. Tom Obryan
You know, you know, you know that you can’t do this anymore. You just can’t do it. You cross the threshold.

00:46:19:07 – 00:46:40:05
Nathan Crane
Yeah. Yeah. I mean, I discovered it was corn for me, and it took me years. I mean, because it wasn’t. I wouldn’t eat corn and then feel sick immediately. It was what I discovered was an accumulation of corn in my diet. And then I would then all of a sudden, these these symptoms would explode, you know, vomiting and diarrhea and just, you know, it was like the flu.

00:46:40:05 – 00:46:58:20
Nathan Crane
And it would happen consistently. And I mean, I went through so many parasite cleanses, you know, fungus cleanses, fasts, you name it, so many different things and tests and all this until it was like stop eating corn. And when I once I kind of figured out, I was like, okay, maybe it’s the corn. I stopped wheat. Long time.

00:46:58:20 – 00:47:22:08
Nathan Crane
You know, it was like, gluten is not good for you. You know, I figured that out years ago, but we’re still eating corn. And for whatever reason, for me, it was the corn and then once I got that out, you know, knock on wood, not a symptom from that in the past couple of years now marvelous granulation. So I wonder if it’s that so could it be the gluten the the gluten protein from that from corn and now it was always sugar and it corn.

00:47:22:08 – 00:47:26:13
Nathan Crane
It wasn’t genetically modified. It was always organic. So I guess it.

00:47:26:23 – 00:47:44:19
Dr. Tom Obryan
Hmm, yeah. There’s some, there is some protein that activated your immune system. Mm. Given that it was always organic. Yeah. Because most corn nowadays is GMO corn. Yup. And it’s loaded with glyphosate and that has a whole world of problems all by itself.

00:47:44:19 – 00:47:51:12
Nathan Crane
And pesticides, herbicides, fungicides, especially like glyphosate. They also tear up the intestinal lining, right?

00:47:52:05 – 00:48:18:15
Dr. Tom Obryan
Yeah. Let me tell you one study that is a reality check and it actually brings some hope of what people can do in the Journal of the American Medical Association in 2019, they published a study from Harvard, and the editors of the Journal made a comment. They said, This is an elegant study using sophisticated biomarkers to prove their point.

00:48:19:16 – 00:48:42:21
Dr. Tom Obryan
Now, the editors of the Journal of the American Medical Association don’t say that very often. They don’t give a stamp of approval to an article, but they did here. So I thought, okay, I can’t argue with this. And they looked at couples going to assisted fertility centers, which I would suspect a large percentage of your audience would be in that category.

00:48:42:21 – 00:49:14:08
Dr. Tom Obryan
They’ve got friends or perhaps themselves. They’ve done this or considering it, and they ruled out all of the known factors that contribute to success or failure. Cigaret smoking, alcohol consumption. Exercise. No exercise. Socioeconomic class, race. They ruled all that out in an elegant way that you couldn’t argue with the science. And they looked at one factor and one factor only.

00:49:15:03 – 00:49:55:23
Dr. Tom Obryan
How many servings of fruits and vegetables was the woman eating a day? And when they looked at that and they divided them into force, the lowest number, the second, the third and the highest number of servings per day of fruits and vegetables. The results were shocking. Everybody knows well, more fruits and vegetables better know if you were in the highest category of fruit and vegetable consumption compared to those in the lowest category of fruit and vegetable consumption, you had an 18% less likelihood of successful implant tation.

00:49:57:18 – 00:50:28:09
Dr. Tom Obryan
And if you did get pregnant, you had a 26% less likelihood of a live birth. You lost the baby to miscarriages and stillbirths more often, much more a quarter more, 26% more. What the more fruits and vegetables I eat, the worse the outcome. Yes. And you can’t argue with the study. It’s in JAMA, the Journal of the American Medical Association.

00:50:28:09 – 00:50:56:16
Dr. Tom Obryan
And the editors made a comment elegant study using sophisticated biomarkers to prove their point. Now, here’s the good news. There was a subgroup of women who were eating organic, and in that category the results were the exact opposite. The more fruits and vegetables you were eating, the better the outcome, the healthier the pregnancy and healthy delivery. And here’s the really good news.

00:50:57:00 – 00:51:34:08
Dr. Tom Obryan
Women were put in the category of organic consumption. If they ate three meals a week. Organic, not three a day. Mm. Three a week. You don’t have to be perfect. You just have to be moving in the right direction. And we think it’s because I think this is my opinion the authors didn’t look into any of that. But my opinion is if these women are eating organic a minimum of three times a week, they probably bought organic shampoo and organic mouthwash and toothpaste.

00:51:34:08 – 00:51:43:19
Dr. Tom Obryan
And they’re doing other things to try and be healthy, which is what you’re all about here on the show is all the little things that you can do to be healthy. Exactly right.

00:51:44:04 – 00:52:16:02
Nathan Crane
Well, you imagine just in, if you’re eating a conventional diet, you think you’re eating healthy, you’re eating fruits and vegetables, which are great, you know, whole grains, legumes, things like that. But they’re non-organic. They literally can have, you know, a hundred plus different pesticide ads in them. And many of these pesticides we know are either probable carcinogens or endocrine disruptors or haven’t been studied long term on their health impacts yet.

00:52:16:02 – 00:52:45:13
Nathan Crane
But they are man made, laboratory synthesized chemicals, which we know in most of those are not great for your health. And then you add on top of that the hundreds of these chemicals, 140,000 plus man made chemicals that have been made in the last 75 years. Many of them are neuroendocrine disruptors. They are endocrine disruptors. They are carcinogenic or probable carcinogenic in your shampoos, your lotions, your toothpaste, all those things.

00:52:45:21 – 00:53:04:20
Nathan Crane
And now you’re swimming in this soup of just toxic chemicals destroying your body from the inside out and the outside in. And then you have someone that goes, You know what? I’m going to eat mostly organic. I’m going to switch my body care products to mostly organic. And you eliminate hundreds and hundreds of chemicals overnight. What do you think’s going to happen to your health?

00:53:05:04 – 00:53:06:20
Nathan Crane
Of course you’re going to get better.

00:53:06:22 – 00:53:25:23
Dr. Tom Obryan
You’re going to have a healthy pregnancy and more success with assisted centers. And, you know, in Europe, they outlaw over 20,000 chemicals. They can’t be brought into the country in any form whatsoever. The U.S., it’s 12.

00:53:26:01 – 00:53:26:16
Nathan Crane
That’s crazy.

00:53:26:17 – 00:53:38:22
Dr. Tom Obryan
20,000 versus 12. It’s all about dollars. It’s all about lobbying. And and allowing the chemical industry to bring in whatever they want.

00:53:39:08 – 00:54:00:02
Nathan Crane
I’d love for you to talk a little bit more about solutions for people when it comes to healing the gut. And this is a specialty of yours. And, you know, I’ve interviewed you on summits and docu series in the past. I know you have a docu series coming up as well, if you talk about that. But what are some solutions, people?

00:54:00:02 – 00:54:09:06
Nathan Crane
Can we talk about a few? But, you know, let’s make it practical and helpful for people, because if all disease begins in leaky gut, then this is really where we should start, right?

00:54:10:23 – 00:54:47:09
Dr. Tom Obryan
That’s right. If that’s the only thing you’re going to do, Mrs. Patient, is build a healthy, diverse microbiome that has more downstream effects and benefits than anything else you could do. Doesn’t matter what vitamins you take, it doesn’t matter compared to putting your attention on building a healthy, diverse microbiome. So there are many, many steps to that. In my I have an online training program for health care practitioners called the Certified Gluten-Free Practitioner Program, and it’s an hour presentation of just study after study after study.

00:54:47:22 – 00:55:15:11
Dr. Tom Obryan
But the basic things to start with, the first and most important thing is to make sure you’re hydrated, that most people, you know, just pinch the back of your hand. If it doesn’t go flat immediately, you’re dehydrated. It should go flat immediately, not stick up and then taper down. And so it’s a third of an ounce of water per pound, healthy water as healthy as you could do per pound body weight.

00:55:15:11 – 00:55:42:08
Dr. Tom Obryan
And if you’re sweating a lot, if you’re doing soreness, which are great for you to get the toxins out of your body, infrared sign it or you’re exercising with a lot of sweat. It goes up to a half ounce of pound, half ounce of water, per pound body weight. So that’s first. And most important is to make sure you’re well hydrated because you have to escort stuff in and you have to escort stuff out after that.

00:55:43:06 – 00:56:18:11
Dr. Tom Obryan
Fruits and vegetables. Organic. Critically. Critically important. And we call it the rainbow diet. It’s the colors of the rainbow that we recommend to you. And most people eat somewhere between five and 12 different fruits or vegetables every week. The same ones we recommend you work up to. The goal is 50 a week, 50 different colors of the rainbow, that concept, you know.

00:56:18:11 – 00:56:50:21
Dr. Tom Obryan
So it’s red tomatoes, blue berries, purple cabbage, green broccoli, you know, and you just keep brussel sprouts. You just keep alternating the fruits and vegetables, mostly vegetables. We’ve categorized fruits and vegetables in the same category. And they’re really not. They’re really not. Our ancestors did need fruit every day. It wasn’t available. Fruit is in the fall in most places of the world.

00:56:51:09 – 00:57:15:00
Dr. Tom Obryan
Fruit is ripe to be picked in the fall. And when our ancestors ate a bunch of fruit, they put on weight. Their fat cells expanded to prepare for the winter. And so the idea of eating a whole lot of fruit every day, well, you know, it depends. You really want to check your blood sugar and make sure that you’re not yo yoing your blood sugar dependent.

00:57:15:01 – 00:57:20:10
Nathan Crane
So easy where you live, right? I mean, you live in Costa Rica, you get eat fruit year round pretty easily then.

00:57:20:10 – 00:57:21:07
Dr. Tom Obryan
Sure, sure.

00:57:21:07 – 00:57:27:05
Nathan Crane
But this same fruit I get the same thing because it’s the same thing. You’re going to eat variety if you’re eating seasonally.

00:57:27:06 – 00:57:48:07
Dr. Tom Obryan
That’s true. That’s true. But I was born and raised in Detroit and my genetics tell me I’m 99% Italian and Greek. So, you know, my ancestors didn’t eat fruit every day. You know, my digestive system is not up for that. I do have a little fruit every day because of where I live. You know, you don’t have to be fanatical about this.

00:57:48:17 – 00:58:13:20
Dr. Tom Obryan
We just have to keep in mind that and the way you can tell, it’s really easy nowadays. You put a CGM on your arm, a continuous glucose monitor, cyclic caffeine patch or a nicotine patch, and your phone will tell you immediately what your blood sugar is. And you wear it for a couple of weeks and you see the impact of the foods that you choose to eat and, the volume of foods and the timing of foods.

00:58:13:20 – 00:58:40:20
Dr. Tom Obryan
And you see, if you’re making your blood sugar, yo, you know that you need to dial that down and keep your blood sugar more stable. If you want vitality in your senior years, if you want to have your biological age be different than your chronological age so that you age gracefully, then you need to be aware of blood sugar.

00:58:40:20 – 00:59:04:03
Dr. Tom Obryan
And that’s a primary for most of us. It’s not an addendum, an afterthought. You know, first, most important water. You have to be hydrated. Critically important. Second, fruits and vegetables. Third, the balance of fruits and vegetables and all of your foods, and especially if you do a lot of fruits. What’s your blood sugar on a on a regular basis?

00:59:04:03 – 00:59:07:11
Dr. Tom Obryan
So the CGM is an easy way now to do that.

00:59:07:17 – 00:59:30:01
Nathan Crane
Can I share with you some about CGM? So yeah, I wanted to experiment with it. I’ve just the last few weeks I’ve been wearing a CGM. I just took it off a couple of days ago and some really interesting things happened, right? So one one caveat I would say for people is be mindful of, you know, when you have a slight glucose spike, there’s nothing wrong with that.

00:59:30:01 – 00:59:47:10
Nathan Crane
When you eat glucose, you know, when you eat glucose, fructose containing foods, carbohydrates, it’s going to go up and it’s going to come down as long as it doesn’t remain in that spike for long periods of time or go above, you know, exponential numbers. I mean, if it’s getting up to like 170, one, 80, 200, you have an issue there.

00:59:47:22 – 01:00:24:12
Nathan Crane
CGM are notorious Leigh bad at I mean with a 20 up to a 20% misreading as well even the best ones I used levels they sent me Dexcom G6 I think it was these like the best ones and even those can have 15 to 20% misreading. So be mindful of that. I would recommend these are all things I learned as I’ve been using CGM, but as I got it and then where you place it too, I had it behind my arm and it had so many errors and then I got it right between that shoulder and the tricep and it was significant, more accurate, and you can test your blood on an actual blood test

01:00:24:12 – 01:00:38:04
Nathan Crane
stripped at the same time to see how accurate really is. That’s going to be your most accurate and that’s how I was I was tracking it right when I ate a pizza. This was a a vegan pizza at a local restaurant. Okay.

01:00:38:11 – 01:00:41:16
Dr. Tom Obryan
And gluten free, gluten free, gluten free.

01:00:41:16 – 01:01:06:16
Nathan Crane
I think it was like a cauliflower crust, lots of veggies, one pizza. We put the vegan cheese on it when we had no cheese. Right. Ate that pizza and my glucose spiked and had a higher number for longer after that pizza than any other thing I’d eaten up to that point. Fruits, rice, white rice, even white rice, tofu, fruits, vegetables.

01:01:06:16 – 01:01:29:09
Nathan Crane
You know, all that. You get a nice little spike comes back down. Every time I eat a normal whole food meal at home, nice little spike comes back down. No problem with that, right? I eat a pizza and if it’s a quote unquote healthy pizza and boom, huge spike and stayed high for quite a while and then back down just shows you how certain foods, you know, can can significantly impact your blood glucose.

01:01:29:09 – 01:01:46:11
Nathan Crane
Now, if I was eating pizza and cheeseburgers on stuff every day, it’d be a concern. And it probably, you know, be concerned about diabetes or heart disease or cancer down the road. But I don’t eat that way. So a pizza once every two or three months out, gluten free with the family, not a big deal if you’re eating organic at home most of the time.

01:01:46:11 – 01:01:46:20
Nathan Crane
Right.

01:01:47:04 – 01:01:59:10
Dr. Tom Obryan
Right, right. I Agree with you on your overview. I completely agree with you on that. Yeah. And so that’s the value of having these kinds of monitoring devices that you go, holy cow, look at that.

01:01:59:18 – 01:02:00:00
Nathan Crane
Right.

01:02:00:03 – 01:02:36:18
Dr. Tom Obryan
And really, really important. All right. So first is water. Mm hmm. Next is fruits and vegetables. Next, Mrs. Patient, when you go shopping, buy a couple of every root vegetable in the store. Organic, of course. But get turnips and parsnips and rutabagas and radishes and sweet potatoes. Not too many white potatoes because they’re affecting your blood sugar. Sweet potatoes, you know, and you have at least one root vegetable every day.

01:02:36:18 – 01:03:11:07
Dr. Tom Obryan
The fiber in root vegetables feeds the good bacteria in your gut. That’s what your bacteria thrives on, is that fiber, that soluble fiber and insoluble both kinds that are in root vegetables. They they love it and they convert the exhaust of their eating produces these things called short chain fatty acids, which are really healthy for us. And they get in your bloodstream and they heal leaky brain and they heal leaky gut and they’ve got so many benefits.

01:03:11:24 – 01:03:38:23
Dr. Tom Obryan
So you eat one root vegetable every day and you alter the root vegetables because every root bat vegetable feeds different families of the good bacteria in the gut. They don’t feed the bad bacteria. They feed the good bacteria. The bad bacteria thrives on whites, white paste, white rice, white bread, white gluten free products. They feed the bad bacteria.

01:03:39:12 – 01:03:40:20
Nathan Crane
And processed sugar. Right.

01:03:41:07 – 01:04:10:06
Dr. Tom Obryan
And processed sugar. Right, right. So you eat one root vegetable every day. Then you go on Google and you type in list of prebiotic foods. And that’s the category of foods that feed the good guys in the gut. They’re called prebiotics. And you print out the list and you have to from the list every day, which means a banana is a prebiotic and onion is a prebiotic, garlic is a prebiotic.

01:04:10:06 – 01:04:38:03
Dr. Tom Obryan
You’re going to learn that there was a lot of foods already in your diet on occasion that are prebiotics, but you just want to be conscious of it and alternate them on a regular basis. Then when we start working with people, we usually give them a prebiotic supplement for a couple of months, not too long. But while we’re transitioning your eating style, let’s make sure you’ve got plenty of the food to encourage more good bacteria next.

01:04:38:03 – 01:05:26:17
Dr. Tom Obryan
When you go shopping, Mrs. Patient, I want you to buy five different types of fermented vegetables sauerkraut, kimchi, miso, fermented beets, curry flavored, whatever you like. But get five different types because when vegetables ferment, they’re producing the good families of bacteria. And when you eat those fermented vegetables, you inoculate your gut with those good bacteria and you alternate them every day because you’ll get five different types so that you’re alternating every once in a while and your kids will like one more than another, probably, which is okay, but you want to alternate them because each vegetable, when it ferments, produces different families of good bacteria.

01:05:27:03 – 01:05:45:21
Dr. Tom Obryan
And you want to inoculate your gut with as many varieties of good bacteria as you can. So eat a little bit. The gold for an adult is get up to about a tablespoon a day, which could be a teaspoon three times a day. Or I just grab a hunk of it and I throw it on my plate for one meal a day.

01:05:46:17 – 01:06:03:12
Dr. Tom Obryan
You know, sometimes you have to work up to it. So you might start with just a little bit some people don’t like fermented vegetables at all, so you just take your spoon, get a little juice from the fermented vegetables and mix it with your mashed potatoes. Can’t even taste.

01:06:03:12 – 01:06:04:00
Nathan Crane
It. Oh.

01:06:04:06 – 01:06:05:23
Dr. Tom Obryan
You’ll get down there. Get down.

01:06:05:23 – 01:06:18:24
Nathan Crane
There. Kimchi. I love. I love a good spicy kimchi. Yeah, coconut. Coconut yogurts. A great one, too. I mean, you got good probiotics in the yogurt, for example. Yeah, sauerkraut, even pickles. Even pickles. Technically, yeah.

01:06:18:24 – 01:06:24:08
Dr. Tom Obryan
There’s a difference between pickles and vinegar, though. And pickles that are fermented. And you want them fermented once.

01:06:25:00 – 01:06:25:16
Nathan Crane
And, you know.

01:06:26:19 – 01:07:03:15
Dr. Tom Obryan
You don’t see obese Koreans very often. They eat kimchi every day, their guts. And many of you have heard the stories and they’re true. The studies are really true. If you take the feces from an obese animal and you inject it into a skinny, skinny animal, the skinny animal gets obese. If you take the feces of a skinny animal and you inject it into an obese animal, the obese animal gets skinny that it’s the bacteria in your gut that have a great influence on your body composition.

01:07:04:08 – 01:07:29:15
Dr. Tom Obryan
So you want to build the good guys in your gut, the diversity of good guys. You don’t just take a pill of a probiotic every day, which is not a bad thing to do, but you can’t limit yourself to that. There’s no diversity there. Right. So and then, of course, misses patient for a few months. I’d like you to take a pill of probiotics while we’re building up your your repertoire of good guys in the gut.

01:07:29:22 – 01:07:59:24
Dr. Tom Obryan
But for a few months to three months should be enough. You know, on that next buy 1015 apples, always organic. Wash them, don’t peel them, cut the seeds out of them, chop them up into chunks and put them in a pot. Add water to about a third the height of the apples. Throw a little cinnamon in there, you throw a little glutamine, you can throw a little Cuban in there.

01:08:00:00 – 01:08:36:05
Dr. Tom Obryan
If you like. Turn it on high and boil for 10 to 15 minutes. You got applesauce, that’s all it takes. And the pectin in applesauce feeds arguably the most valuable enzyme in your gut called intestinal alkaline phosphatase IAP, which lowers high cholesterol, lowers high triglycerides, stabilizes insulin sensitivity, reduces insulin resistance, locks up LPs, these bad bacteria so they can’t get into your bloodstream.

01:08:37:01 – 01:08:59:05
Dr. Tom Obryan
The list goes on and on of what intestinal alkaline phosphatase and you increase it by having a little pectin and homemade apple sauce is a great source of pectin and so you not to store bought applesauce it’s homemade. Have your kids help you make it it’s simple they’re involved in preparing food at that you know that way. And applesauce tastes great.

01:08:59:16 – 01:09:16:02
Dr. Tom Obryan
You know you you can add a few raisins to it if you want and you have a couple of tablespoons a day. You can have more if you want, but at least a couple of tablespoons a day, you’re just feeding that environment in your gut to make it a healthier, stronger environment.

01:09:16:09 – 01:09:20:22
Nathan Crane
Now is our benefit. And you the applesauce versus just eating a raw apple every day?

01:09:22:10 – 01:09:45:21
Dr. Tom Obryan
Well, you can do it’s two apples a day every so it really should be. And, you know, a doctor, an apple a day keeps the doctor away. Know two apples a day, keep the doctor away. And so you know, you cross out the are and put the number two there on a bumper sticker, two apples a day, keep the doctor away and it really works.

01:09:45:21 – 01:10:17:02
Dr. Tom Obryan
Yeah, yeah. Braeburn, red and Gala are the three most impactful varieties that I’ve seen. Always organic, because apples have been on the Dirty Dozen every year for many, many years. They use lots of chemicals on apples. And you don’t want all those chemicals. So that’s a good basic overview of how you get started in building a healthier microbiome.

01:10:17:13 – 01:10:38:06
Nathan Crane
Yeah, that’s super helpful. Plenty, plenty of great takeaways there. Now you have people want to go deeper with you and your work. I know you’ve got an upcoming docu series. You’ve put a lot of time and energy into and I know you’ve got consulting to your website. You do a lot. You work with patients all over the world.

01:10:38:06 – 01:10:41:13
Nathan Crane
Can you talk a little bit about your upcoming as well?

01:10:41:22 – 01:11:10:19
Dr. Tom Obryan
Yeah, thank you. Thank you so much. Yeah, we’ve spent the last year on this. I’m not a professional producer of these events. This would be my third one in 11 years. And it’s paradigm shifting and it’s all about this concept of low grade chronic inflammation under the surface that’s there for years before you ever have a symptom. And it’s called the inflammation equation, and it’s the inflammation equation dot com.

01:11:11:13 – 01:11:48:06
Dr. Tom Obryan
And you what, what you’re going to learn are all of the little steps. It’s an hour a day for nine days, not too long with a lot of handouts. I’ve got a video that does the entire I think it’s almost an hour on building healthy microbiome. It’s all the little things, you know, for example, I forgot to mention three or four walnuts a day have a great impact on increasing one of the really good bacteria your gut called echo or here you know so you just have a few just three or four solid takes every day or multiple times.

01:11:48:07 – 01:11:48:19
Dr. Tom Obryan
What would be.

01:11:49:04 – 01:11:53:01
Nathan Crane
Useful for those acronyms. Yeah, not necromancer, right?

01:11:53:03 – 01:12:23:09
Dr. Tom Obryan
Just Claire Ecker a.k.a E.R. a.k.a. Mantia. It’s it’s arguably the most dominant good guy in your gut. And it helps to heal leaky brain and leaky gut many, many benefits to having adequate amounts of akkermansia. But in our event we’ve got lots of handouts. We’ve got the handouts from NASA on houseplants too. Six inch houseplants in a ten by ten room absorbs 74% of the toxins in the air.

01:12:24:05 – 01:12:48:18
Dr. Tom Obryan
So you clean up your air in your house. We’re teaching people about all of the things to do, step by step things. And when you register at the inflammation equation account, the gift that we’re giving everybody is the full interview. So because I’ve interviewed over 60, 64, I think it is world class scientists like Schonfeld that I talked about earlier and and many others.

01:12:48:18 – 01:13:13:19
Dr. Tom Obryan
I went to nine different countries to interview these people, and we put the series together every day as a story. So there’s 9 minutes of scientist and 8 minutes of this one and 14 minutes of this one is 6 minutes of this patient. And it’s the story for the day, like inflammation for the day or about food choices for the day, or about sleep and how important sleep is for the day.

01:13:14:07 – 01:13:40:05
Dr. Tom Obryan
And you get all these pearls in there with it on a daily basis. But the interviews themselves were all over an hour, you know, but we’re not showing 64 hours of all that. But they’re available if somebody wants them. But I’m giving you the full interview with Fran Drescher, the nanny. When you register and you just you see what an incredible human being she is.

01:13:40:18 – 01:14:06:07
Dr. Tom Obryan
And, you know, she was diagnosed with cancer 23 years ago, uterine cancer. And she founded Cancer Schmancer as a result of that. And she talks about you make your home, your sanctuary area, your home is first, your body is your sanctuary. And she said, you know, when I was smoking, when my teenager in my early twenties, I was smoking.

01:14:06:07 – 01:14:30:18
Dr. Tom Obryan
And one day I realize, why am I poisoning my lungs? Why don’t I love my lungs, you know? And she started laughing, that laugh of hers and that new York accent of hers, which is so engaging. But she realized, you know, I was treating my lungs very, very poorly. And she you treat your body like a sanctuary and you learn how to take care of it and and it will take care of you.

01:14:30:18 – 01:14:41:04
Dr. Tom Obryan
And she looks great. You know, she’s in her my eyes film her mid sixties maybe, I don’t know. Somewhere it’s always dangerous to try to guess a woman’s age.

01:14:41:20 – 01:14:50:20
Nathan Crane
But just try and guess anybody’s age. Man, I’m terrible at it. I’m. Yeah, I’m like, yeah, you’re what, forties? Like, I’m 27. I’m like, Oh, I’m sorry.

01:14:51:03 – 01:14:52:14
Dr. Tom Obryan
Sorry. Right, right.

01:14:52:14 – 01:14:55:12
Nathan Crane
Never mind. I’m not making guesses anymore. I’m sorry.

01:14:55:12 – 01:15:15:00
Dr. Tom Obryan
Yeah, but you know, I’m giving everybody that full interview with Fran because it’s so empowering about she said that you just take once you put one foot in front of each other, how do you walk? You walk with one foot in front of the other hand. You know, she has that laugh of hers, which I really can’t mimic, but it’s just so funny.

01:15:15:00 – 01:15:27:17
Dr. Tom Obryan
But she says, you put you put one foot in front of the other. That’s how you change the direction of your life. And so that’s our event. It’s a nine day event and can find more at the inflammation equation dot com.

01:15:28:02 – 01:15:36:01
Nathan Crane
With the word the is in the domain inflammation equation dot com and it’s free, right? It’s totally free.

01:15:36:01 – 01:15:37:18
Dr. Tom Obryan
It’s all free. Everything’s free.

01:15:37:19 – 01:15:59:17
Nathan Crane
Awesome. Beautiful. I love it. There you go, guys. Go check it out. The inflammation equation dot com. Dr. Tom. Hey, man, awesome having you on the podcast. This was this was really a wonderful, wonderful interview and you delivered a tremendous amount of value. Appreciate you and appreciate you coming on.

01:16:00:11 – 01:16:03:20
Dr. Tom Obryan
Thank you, Nathan. Appreciate YouTube, man. It’s great to see you again.

01:16:04:04 – 01:16:06:13
Nathan Crane
Absolutely. Good to see you, too. Take care.

01:16:07:10 – 01:16:07:22
Dr. Tom Obryan
Bye bye.