Head over to https://nathancrane.com/podcast/ to learn more about preventing Alzheimer’s and dementia!
In this eye-opening interview, Dr. Tom O’Bryan discusses the shocking rise in Alzheimer’s diagnoses, even among younger populations, and how chronic inflammation plays a key role.
Find out how simple lifestyle changes and the right tests, like the Neural Zoomer Plus, can help protect your brain and reduce inflammation.
Don’t wait—take action now to safeguard your future!
Your host, Nathan Crane, is a Certified Holistic Cancer Coach, Best-Selling Author, Inspirational Speaker, Cancer-Health Researcher and Educator, and 20X Award Winning Documentary Filmmaker with Over 15 Years in the Health Field.
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#Alzheimers #BrainHealth #ChronicInflammation
Audio Transcript
(This transcript was auto-generated so there may be some errors)
00:00:00:02 – 00:00:34:16
Nathan Crane
Today we are joined by Dr. Tom O’Brien, who is a world renowned expert on autoimmunity, everything autoimmune. You’ve probably seen some of his documentaries, series, his summits, a lot of the work he does through the Dr. Rt.com on helping educate people, patients and doctors around the underlying root causes of inflammation, chronic inflammatory diseases in the body, which autoimmunity is directly stem from chronic inflammation, not to mention cancer, diabetes, heart disease, just about every major disease that we experience today.
00:00:34:17 – 00:00:58:01
Nathan Crane
And I was speaking with Dr. Tom. This is probably, what, six or seven months ago, I think you were on I think one of my programs. We were doing an interview and we were talking about the brain and how chronically inflamed. So many people’s brains are and how, you know, this is contributing to Alzheimer’s and dementia and just how those neurological diseases are exploding.
00:00:58:01 – 00:01:24:05
Nathan Crane
And you had mentioned a specific test called the neural zoomer plus. And you said you said I should do it. And it’s something that pretty much everybody should do to see where the inflammation levels are and the triggers are in your brain, to see basically the health of your brain and then be able to have some guidance on what to do to help prevent some of these diseases down the road and help improve the health of your brain.
00:01:24:05 – 00:01:45:15
Nathan Crane
I said, okay, cool, let’s do it. So and and you said, if you do the test, I’ll come back on with you and actually go over it and share all the details and results with you. So I did the test. The test actually was back in July. So we’re doing this a few months later at the time we’re recording this, but I got the results.
00:01:46:08 – 00:02:11:00
Nathan Crane
I don’t understand just about anything about it. And I know you have prepared a an entire presentation to go through it. So we’re going to look literally under the hood into my brain, going to get into my skull and look at my brain and see what’s going on. And this is somebody who, you know, has been who who used to be, I would say, living a very, very unhealthy life.
00:02:11:10 – 00:02:43:24
Nathan Crane
And then about 18 years ago, 19 years ago, started shifting. And over the last decade plus 15 plus years, you know, primarily organic, plant based, lots of fresh foods, whole foods, certainly not perfect any of it. But so, you know, sauna, exercise, size, sleep, meditation, all the things that we teach, infrared, you know, ice baths, all the things in terms of helping to prolong health and longevity and vitality, as well as doing detoxes and cleanses and heavy metal detox and all these things.
00:02:43:24 – 00:03:07:23
Nathan Crane
And even so, living, you know what I would say is a pretty incredibly healthy life from our modern standards. I know we’re going to see some things in this report that show some inflammation and some things to watch out for. So I’m interested to see what’s there and then how people watching this can learn, you know, what they need to do to help protect their brain.
00:03:07:23 – 00:03:14:07
Nathan Crane
So anyway, Dr. Tom, thanks for doing this. Thanks for encouraging me to do this and thanks for coming on the podcast to talk about it.
00:03:15:05 – 00:03:36:24
Dr. Tom O’Bryan
Thanks, Nathan. Thanks so much. I’ve got a couple of questions for you to begin with, and the first one is as knowledgeable as you are, and that was a great summary of how you’ve transitioned your life into a much healthier life in the last 18 years. When you saw those test results, what happened for you?
00:03:40:05 – 00:04:02:01
Nathan Crane
I mean, you know, when I see like the the yellows and, you know, there’s a lot of greens, right? There’s a lot of in ranges and then there’s a number of yellows and there’s some reds, which are obviously things we’re going to get into of like, okay, these are some things we need to look at. I looked at it and I thought, actually, you know, the amount of greens that are there is a pretty high amount, meaning things that are in reference.
00:04:02:01 – 00:04:05:01
Nathan Crane
Right? And I thought, okay, so I’m obviously doing something right.
00:04:05:19 – 00:04:06:17
Dr. Tom O’Bryan
But any time, right?
00:04:07:01 – 00:04:34:08
Nathan Crane
Hmm. Yeah. And then any time you see some reds and some yellows, you’re like, okay, I need to pay attention. And so I didn’t feel like, you know, I’ve done a number of, you know, blood tests, extensive blood tests over the years because I do different kinds of experiments and I’ll document it. And so, you know, when I look at my extensive, you know, inflammatory markers and blood tests and so forth, most of the time 80 or 90% of the time, everything’s in range.
00:04:34:08 – 00:04:54:18
Nathan Crane
But there’s always something you know, there’s always something that’s out of range that needs to be looked at. And I’ve just accepted that. That’s the modern world we live in. You know, what we do is we just have to do what we can to combat and, you know, not worry so much about it, but take action to to live the healthiest that we can, I think.
00:04:55:04 – 00:04:58:14
Dr. Tom O’Bryan
Brilliant. That’s a great, great overview to have.
00:04:58:14 – 00:04:59:04
Dr. Tom O’Bryan
And for.
00:04:59:04 – 00:05:07:02
Dr. Tom O’Bryan
Those that are not as experienced in reading test results as you are green, yellow, red is common with most.
00:05:07:02 – 00:05:08:04
Dr. Tom O’Bryan
Tests, most.
00:05:08:04 – 00:05:27:18
Dr. Tom O’Bryan
Functional tests. Green means you’re good to go. Everything’s great. Yellow means you’re going through a flashing yellow light. What does that mean? Well, it means you slow down and you look both ways to see if there’s a car coming. Meaning something’s not. This is a danger zone. You might want to be looking at this. And red means stop.
00:05:28:09 – 00:05:38:06
Dr. Tom O’Bryan
Stop and address it. Well, how do you address it? Well, that’s what you have to find out. You know, what are the areas that are in the red zone and how do I address it? So that’s a general.
00:05:38:06 – 00:05:40:11
Dr. Tom O’Bryan
Overview of how to look at all of this.
00:05:41:21 – 00:05:57:12
Dr. Tom O’Bryan
And in this test, you know, we’re going to talk a lot about why this test is important for me. I won’t see a patient unless they do this test. And you’re going to learn here. You’ll see some of the science that it’s the IRT, one of the earliest markers.
00:05:57:20 – 00:05:58:05
Dr. Tom O’Bryan
Of.
00:05:58:16 – 00:06:00:19
Dr. Tom O’Bryan
Inflammation causing.
00:06:00:20 – 00:06:05:04
Dr. Tom O’Bryan
Tissue damage in your body. And while you feel fine.
00:06:05:23 – 00:06:09:17
Dr. Tom O’Bryan
Now, the importance of that concept is that we know.
00:06:09:24 – 00:06:12:14
Dr. Tom O’Bryan
That Alzheimer’s.
00:06:13:05 – 00:06:17:16
Dr. Tom O’Bryan
Develops over 25 to 30 years. While you feel fine.
00:06:19:01 – 00:06:21:13
Dr. Tom O’Bryan
You feel fine. But the.
00:06:21:13 – 00:06:22:14
Dr. Tom O’Bryan
Mechanisms going.
00:06:22:14 – 00:06:23:12
Dr. Tom O’Bryan
On and.
00:06:23:12 – 00:06:42:09
Dr. Tom O’Bryan
That’s really important to grab on to. So it doesn’t matter how you feel right now in terms of do I look to see if there’s underlying mechanisms going on? It doesn’t matter how you feel. And we spoke on your last podcast, Blue Cross Blue Shield, published in February of 20.
00:06:43:00 – 00:06:47:06
Dr. Tom O’Bryan
20, not 2019, February No, 2020.
00:06:47:07 – 00:06:54:18
Dr. Tom O’Bryan
February of 2020. They said, we’ve got a problem here, but no one paid attention to it because that’s when the virus came.
00:06:54:18 – 00:06:54:24
Dr. Tom O’Bryan
Out.
00:06:56:16 – 00:07:09:01
Dr. Tom O’Bryan
That they said, you know, in the previous four year period, there was a 407% increase in the diagnosis of Alzheimer’s in 30 to 44 year olds in.
00:07:09:02 – 00:07:11:17
Nathan Crane
400% increase, there is.
00:07:11:18 – 00:07:13:17
Dr. Tom O’Bryan
407%.
00:07:13:22 – 00:07:15:12
Nathan Crane
407% for.
00:07:15:23 – 00:07:16:14
Dr. Tom O’Bryan
Years.
00:07:17:24 – 00:07:33:16
Nathan Crane
That’s that’s very it’s crazy to hear and it’s actually in alignment with the cancer increases. Well, there was a recent study that came out that, you know, cancer in younger people has gone up something like 79%. We’re talking 30 year olds. 40 year olds, you know. Yeah, yeah, yeah.
00:07:33:16 – 00:07:55:04
Dr. Tom O’Bryan
And there’s some discussion that maybe some vaccinations have contributed to that. Maybe, maybe not. But this Blue Cross Blue Shield was before this pandemic. So it had nothing to do with anything except lifestyle. And so it’s important for everyone to have a grasp of this particular topic because it’s so prevalent now.
00:07:55:22 – 00:07:58:11
Dr. Tom O’Bryan
So let’s jump in and let.
00:07:58:11 – 00:08:18:21
Dr. Tom O’Bryan
Me share screen here. And I would suggest that people write down their questions because the next slide is going to give you a next question or the next slide or get the next question. So write them down when they come up for you or on your phone, or get a piece of paper and let’s take a look at this thing.
00:08:18:21 – 00:08:25:01
Dr. Tom O’Bryan
So I appreciate the opportunity to do this. My my goal is to bring awareness to people.
00:08:25:09 – 00:08:27:10
Dr. Tom O’Bryan
To check that the.
00:08:27:10 – 00:08:31:15
Dr. Tom O’Bryan
Rule in functional medicine is test. Don’t guess.
00:08:31:15 – 00:08:31:24
Dr. Tom O’Bryan
You.
00:08:31:24 – 00:08:40:00
Dr. Tom O’Bryan
Know, that you can’t guess whether you’re functioning adequately and reducing the amount of tissue degeneration.
00:08:40:11 – 00:08:40:24
Dr. Tom O’Bryan
Before.
00:08:40:24 – 00:08:43:21
Dr. Tom O’Bryan
You get symptoms. You can’t guess. Yes. Why? I feel.
00:08:43:21 – 00:08:44:22
Dr. Tom O’Bryan
Fine. Well.
00:08:45:10 – 00:08:49:22
Dr. Tom O’Bryan
But wait. Every autoimmune disease is going up 49% a year.
00:08:50:17 – 00:08:52:13
Dr. Tom O’Bryan
Every one of them every year.
00:08:52:20 – 00:08:54:07
Dr. Tom O’Bryan
And as you said, cancer is going.
00:08:54:07 – 00:08:54:24
Dr. Tom O’Bryan
Through the roof.
00:08:55:16 – 00:09:22:14
Dr. Tom O’Bryan
So there’s something going on that people are not aware of. So the reason I’m doing this is because this is my boss. And Einstein said the problems we have today cannot be solved with the same level of thinking that created the problem. And so our goal with our son, who is now almost four, is that he learns to think outside the box.
00:09:23:09 – 00:09:37:08
Dr. Tom O’Bryan
He thinks for himself. He explores, he asks questions. We try our best to guide him and actually not parent him, but rather steward him so that he’s thinking for himself.
00:09:37:24 – 00:09:38:08
Dr. Tom O’Bryan
And.
00:09:38:08 – 00:09:54:03
Dr. Tom O’Bryan
Always taxing himself a little bit more, you know, just thinking for himself and thinking for himself. That’s our goal. And this is a book that everyone should read. It came out back in the sixties and there’s a revised version of it, but hands.
00:09:54:04 – 00:09:55:23
Dr. Tom O’Bryan
So he was the.
00:09:56:04 – 00:09:59:04
Dr. Tom O’Bryan
Man, the researcher who coined the word stress.
00:09:59:15 – 00:10:01:11
Dr. Tom O’Bryan
With health issues.
00:10:01:21 – 00:10:09:10
Dr. Tom O’Bryan
Before that, the word stress was associated with steel girders and how much pressure they could take before they crack.
00:10:09:24 – 00:10:11:04
Dr. Tom O’Bryan
And he put it.
00:10:11:04 – 00:10:14:10
Dr. Tom O’Bryan
In perspective for our own bodies and what happens over.
00:10:14:19 – 00:10:18:04
Dr. Tom O’Bryan
A lifetime of too much pressure.
00:10:18:04 – 00:10:29:08
Dr. Tom O’Bryan
On the girders, too much stress, and how it is a primary set up in the development of every single disease. And I loved his.
00:10:30:16 – 00:10:31:11
Dr. Tom O’Bryan
Dedication.
00:10:31:11 – 00:10:33:20
Dr. Tom O’Bryan
Here because it relates so much.
00:10:33:20 – 00:10:34:17
Dr. Tom O’Bryan
To what we’re.
00:10:34:17 – 00:10:35:05
Dr. Tom O’Bryan
Doing.
00:10:35:05 – 00:10:36:23
Dr. Tom O’Bryan
Today and what we’re talking about.
00:10:37:08 – 00:10:42:02
Dr. Tom O’Bryan
Nor so naive as to think they can do so without intellectual effort.
00:10:42:16 – 00:10:42:23
Dr. Tom O’Bryan
You know.
00:10:43:00 – 00:10:45:15
Dr. Tom O’Bryan
We’ve got to be taking a look at things.
00:10:45:24 – 00:10:47:22
Dr. Tom O’Bryan
That we may not.
00:10:47:22 – 00:10:49:00
Dr. Tom O’Bryan
Be familiar with.
00:10:49:17 – 00:10:50:10
Dr. Tom O’Bryan
And see if.
00:10:50:15 – 00:10:56:04
Dr. Tom O’Bryan
It relates to us. So this presentation is a paradigm expanding.
00:10:56:11 – 00:10:59:16
Dr. Tom O’Bryan
Thought provoking engagement on the path.
00:10:59:23 – 00:11:02:01
Dr. Tom O’Bryan
To setting priorities in getting.
00:11:02:01 – 00:11:02:15
Dr. Tom O’Bryan
Healthier.
00:11:03:18 – 00:11:09:15
Dr. Tom O’Bryan
So I encourage you to write down your questions and your thoughts so that they can be addressed.
00:11:10:03 – 00:11:22:03
Nathan Crane
Also, I just want to mention, I don’t know if we’ve just mentioned the the name of that book. The name of that book was The Stress of Life for people who are only listening on iTunes, Spotify and so forth. They want to see.
00:11:22:14 – 00:11:22:21
Dr. Tom O’Bryan
Good.
00:11:22:21 – 00:11:26:07
Nathan Crane
Images. Yeah, it was called The Stress of Life.
00:11:26:08 – 00:11:47:19
Dr. Tom O’Bryan
Stress of life, right. It’s just a classic. You know, he explains to us things like a young man that unfortunately dies of trauma, his adrenal glands, they sit on top of the kidneys. The adrenal glands are the size of a walnut. A young man that dies, unfortunately, of disease, same age. His adrenal glands are the size of a.
00:11:47:19 – 00:11:48:06
Dr. Tom O’Bryan
Peanut.
00:11:49:08 – 00:12:20:12
Dr. Tom O’Bryan
They’ve shriveled up and the adrenal glands can’t handle the stress of life anymore. And so he talks about how we wear down. It’s really a great primer to understand the wear and tear on our bodies from the life that we’ve lived so far. So for years, if I read a study that was what? What did they say? I would take the front page of that study or a graph from the study, and I tape it on the ceiling of my bedroom.
00:12:21:12 – 00:12:29:09
Dr. Tom O’Bryan
So when I go to sleep at night and oh, yeah, oh yeah. And then sometimes I’d think about I’d have an idea and their topic.
00:12:30:01 – 00:12:32:04
Dr. Tom O’Bryan
You know, and I had.
00:12:32:04 – 00:12:33:16
Dr. Tom O’Bryan
A little pen and paper next to.
00:12:33:16 – 00:12:36:04
Dr. Tom O’Bryan
My bed and I write.
00:12:36:04 – 00:13:11:24
Dr. Tom O’Bryan
It down and in the morning say, Oh, that’s right, I did too. That’s right. And what I was doing was giving myself permission to think outside the box, giving myself permission to think about areas that kind of caught my attention. And nowadays I recommend people, you know, whatever the idea is or if it’s a doctor. The study that you’ve read or you’ve heard about or the article, tape it on your refrigerator door, you don’t have to tape it on the ceiling of your bedroom or on the mirror in your bathroom somewhere where you’re going to see it.
00:13:12:15 – 00:13:30:06
Dr. Tom O’Bryan
And then you’ll be driving down the road and you’re driving down the road and all of six. Oh, you know, on that, I wonder if that means and you just start giving yourself permission to think a little differently to expand how you look at a particular topic.
00:13:30:20 – 00:14:05:02
Nathan Crane
And, you know, I saw on that I love that idea because, you know, there are so many interesting studies. I’ve looked at, you know, thousands of studies over the years. I’m sure you’ve looked at so many more. And there are some that just stick out in my mind so profoundly. Like that really make you think deeply. There was a there was a number of studies that were done on cancer cells in Petri dishes where literally they brought in qigong master practitioners who what they did was practice qigong, sending lifeforce energy from their body to the petri dish.
00:14:05:11 – 00:14:35:07
Nathan Crane
And they had, you know, placebo controlled. So they had petri dishes that they didn’t send that qigong energy to from the body and ones that they did. And they saw the ones that they were. The Qigong teacher was sending the energy to the cancer cells in the petri dish literally killed the cancer cells, created apoptosis in those cells and destroyed the cancer cells and the normal cells, you know, the cancer cells in the other dish, obviously nothing happened because they didn’t do anything to it.
00:14:35:16 – 00:14:48:12
Nathan Crane
And those are like those are the kinds of studies that I would print. Same thing. I’ve printed those out. I’ve saved them in Dropbox. I pulled them up in my, you know, screen and looked at it from time to time. I’m like, this is so fascinating. Yes.
00:14:48:20 – 00:14:49:22
Dr. Tom O’Bryan
Yes. Right.
00:14:50:13 – 00:14:53:19
Dr. Tom O’Bryan
And I encourage everyone to do that.
00:14:53:19 – 00:14:55:11
Dr. Tom O’Bryan
And on your refrigerator.
00:14:55:23 – 00:15:13:24
Dr. Tom O’Bryan
The mirror, your bathroom, anywhere that you would just see it. And the end result is somewhere down the road, maybe in an hour, maybe three days, maybe a week. You’re going to think about that in a new way. You’re going to have another thought about that particular fact.
00:15:14:10 – 00:15:15:16
Dr. Tom O’Bryan
That you were reading.
00:15:16:09 – 00:15:34:17
Dr. Tom O’Bryan
Because, you know, our goal here is to dove in. It’s just to dove in to whatever topic captures your interest so that you can learn enough on that particular topic to feel competent in it. And it expands your realm, your horizons every single time.
00:15:35:19 – 00:15:36:02
Dr. Tom O’Bryan
Now.
00:15:37:01 – 00:15:42:06
Dr. Tom O’Bryan
Aldous Huxley made a quote a number of years ago that resonates today. So much.
00:15:42:24 – 00:15:43:10
Dr. Tom O’Bryan
Medical.
00:15:43:10 – 00:16:24:14
Dr. Tom O’Bryan
Science has made such tremendous progress that there’s hardly a healthy human left, and that’s not some cutesy little joke. The science behind it is pretty jaw dropping. Life expectancy has increased by three decades since the mid 20th century, since the 1950s, 1960s. But parallel health span is much slower. It has increased at the same rate. And when you look at this graph, for those that can see the graph, you see that the population on the planet in 1950 was about two 2 billion.
00:16:25:02 – 00:16:42:00
Dr. Tom O’Bryan
Now it’s about just over 6 billion. And you look at the percentage of the population that is less than 70 and older than 70. And you see somewhere around 1975 or so, there was just this.
00:16:42:00 – 00:16:44:08
Dr. Tom O’Bryan
Skyrocket of people.
00:16:44:08 – 00:16:46:24
Dr. Tom O’Bryan
Over 70 as a percentage.
00:16:47:08 – 00:16:48:22
Dr. Tom O’Bryan
Of the total population.
00:16:49:11 – 00:16:52:23
Dr. Tom O’Bryan
And now we’ve got so many more people.
00:16:53:09 – 00:16:53:18
Dr. Tom O’Bryan
On the.
00:16:53:18 – 00:17:08:14
Dr. Tom O’Bryan
Blue line, which means over 70 years old than ever before in history. And as you get older, you get sicker. Most people get sicker. So there’s more sick people. Every autoimmune disease is going up 4 to 9% a year.
00:17:09:01 – 00:17:09:20
Dr. Tom O’Bryan
Every one of them.
00:17:10:11 – 00:17:14:13
Dr. Tom O’Bryan
Because there’s more elderly people and there’s more toxicity, were exposed.
00:17:14:13 – 00:17:14:21
Dr. Tom O’Bryan
Too.
00:17:15:11 – 00:17:52:10
Dr. Tom O’Bryan
But this is an interesting concept to understand why there’s so much more disease than ever before. There’s more old people and they’ve lived a lifestyle exposed to so many toxins that their bodies are breaking down. The societal triumph of longevity is plagued with debilitating morbidity, meaning getting sick usually towards the end of life is accentuated, and the gap between total life span and healthy life span continues to get wider.
00:17:52:10 – 00:18:20:16
Dr. Tom O’Bryan
Males live on average to 78.8 years. That’s the average. But the average healthy male life expectancy is 62.4. That means the last 16 and a half years of a man’s life is with disabilities in poorer health, women live a little bit longer. They lived until about 83 and it’s the last 20 years of their life.
00:18:21:00 – 00:18:25:06
Dr. Tom O’Bryan
Are in poorer health. I don’t want to be in a.
00:18:25:06 – 00:18:36:13
Dr. Tom O’Bryan
Wheelchair or, you know, have a stroke in half. My body is not working so well anymore. But these are the numbers of what’s happening or diabetes and and cardiovascular diseases.
00:18:36:13 – 00:18:39:03
Dr. Tom O’Bryan
And where I can’t walk up a hill or.
00:18:39:12 – 00:18:40:14
Dr. Tom O’Bryan
Whatever, the.
00:18:40:19 – 00:18:41:09
Dr. Tom O’Bryan
Morbidity.
00:18:41:11 – 00:18:45:00
Dr. Tom O’Bryan
Is that we’re we’re suffering from, there’s more.
00:18:45:00 – 00:18:46:11
Dr. Tom O’Bryan
Of it for people now.
00:18:46:11 – 00:18:55:24
Dr. Tom O’Bryan
Than ever before in history. One fifth of an individual’s life is lived with morbidity. And I propose.
00:18:56:16 – 00:18:57:19
Dr. Tom O’Bryan
That a.
00:18:57:19 – 00:18:58:17
Dr. Tom O’Bryan
Therapeutic.
00:18:58:17 – 00:18:59:10
Dr. Tom O’Bryan
Vision.
00:18:59:21 – 00:19:16:11
Dr. Tom O’Bryan
For all of us is to reduce the distance between your total life span and your healthy life span. So if you reduce that distance, you’ve got more healthy years before you go into disability.
00:19:17:08 – 00:19:19:03
Dr. Tom O’Bryan
And if you think about that.
00:19:19:03 – 00:19:22:10
Dr. Tom O’Bryan
That just kind of makes sense. But if you put that concept on your.
00:19:22:10 – 00:19:24:13
Dr. Tom O’Bryan
Refrigerator about.
00:19:24:13 – 00:19:29:19
Dr. Tom O’Bryan
Increasing your healthy life span, I don’t know if you’re going to increase your total lifespan. I don’t know.
00:19:29:23 – 00:19:32:19
Dr. Tom O’Bryan
Maybe, maybe not. You know, but the number.
00:19:32:19 – 00:19:40:05
Dr. Tom O’Bryan
Of years that you’re disabled, you certainly can reduce that and increase the number of years that you have full.
00:19:40:11 – 00:19:41:24
Dr. Tom O’Bryan
Health and vitality.
00:19:42:05 – 00:20:10:21
Dr. Tom O’Bryan
You certainly can do that. So when do these diseases begin? There’s a couple of basic concepts here that will help you in understanding how to increase your healthy lifespan. And the first is that the center for Disease Control tells us that 14 of the 15 top causes of death in the world are chronic inflammatory diseases. It’s always.
00:20:10:21 – 00:20:11:16
Dr. Tom O’Bryan
Inflammation.
00:20:12:18 – 00:20:42:07
Dr. Tom O’Bryan
Except unintentional injuries and accident. Everything else is an inflammatory disease. It’s always inflammation. So how important is that? If you want to extend your healthy lifespan and inflammation is the mechanism that’s causing whatever disease you get, it becomes critically important that this becomes a priority for you to learn how to reduce the amount of inflammation you.
00:20:42:07 – 00:20:42:15
Dr. Tom O’Bryan
Have.
00:20:43:16 – 00:20:51:04
Dr. Tom O’Bryan
This drawing. And for those of you that are listening only, I’ll describe it. I saw this drawing and I started.
00:20:51:04 – 00:20:52:20
Dr. Tom O’Bryan
Drawing and I laughed.
00:20:53:04 – 00:21:14:14
Dr. Tom O’Bryan
And I called the author, Your name is David Ferdman. He’s at Stanford. And I called to introduce myself. So, you know, I saw your graph in that article and I started drooling. So he started laughing too. And I said, It’s just brilliant because he’s got three gears next to each other and they all overlap the the spindles on the gears overlap.
00:21:14:14 – 00:21:23:07
Dr. Tom O’Bryan
So if you turn the gear on the left, it turns the one in the middle at the same time. And when the one in the middle turns, it turns the one on the right. At the same.
00:21:23:07 – 00:21:24:08
Dr. Tom O’Bryan
Time they.
00:21:24:08 – 00:21:44:20
Dr. Tom O’Bryan
All move together. Now on the left, the gear is how we live our lives. If we get chronic infections or if we don’t exercise, or if we’re packing extra weight and we’ve got obesity, or if we have a bad gut, too many bad guys in the gut called dysbiosis or the type.
00:21:44:20 – 00:21:45:18
Dr. Tom O’Bryan
Of foods we.
00:21:45:18 – 00:21:47:09
Dr. Tom O’Bryan
Eat. These are all spindles.
00:21:47:18 – 00:21:48:09
Dr. Tom O’Bryan
And the.
00:21:48:09 – 00:21:50:00
Dr. Tom O’Bryan
Gear on the left side.
00:21:50:06 – 00:21:51:03
Dr. Tom O’Bryan
Or increased.
00:21:51:03 – 00:22:02:22
Dr. Tom O’Bryan
Stress hormones or not good quality sleep or the accumulation of toxins in our body lead, mercury, arsenic, organic compounds, glyphosate, all of that stuff.
00:22:03:05 – 00:22:04:23
Dr. Tom O’Bryan
Mold. So those are.
00:22:04:23 – 00:22:42:21
Dr. Tom O’Bryan
The spindles that the gear and the left. And with that turns, it automatically activates the middle gear, which is an immune system, active aided to protect you from whatever that thing is. And your immune system starts producing inflammation. And when that gear turns, it turns the gear on the right. And that’s how we manifest our condition, whether it’s a neurodegenerative disease, an autoimmune disease, depression, cancer, cardiovascular disease, diabetes, osteoporosis, it doesn’t matter.
00:22:43:09 – 00:23:09:18
Dr. Tom O’Bryan
The disease doesn’t matter. Let me back that up to that picture again, because it’s every disease occurs this way. I can’t think of one that doesn’t. They all occur because of excess inflammation, trying to protect you from something that turned activate your immune system, which then is the contributor or damaging the tissue over time.
00:23:09:24 – 00:23:11:11
Dr. Tom O’Bryan
While you feel fine.
00:23:12:00 – 00:23:17:23
Dr. Tom O’Bryan
You didn’t get cancer when you got the diagnosis. You had the cancer developing for years before that.
00:23:19:05 – 00:23:19:17
Dr. Tom O’Bryan
And then.
00:23:19:17 – 00:23:22:14
Dr. Tom O’Bryan
Flares up because you’ve killed off so much tissue.
00:23:23:03 – 00:23:23:09
Dr. Tom O’Bryan
Or.
00:23:23:09 – 00:23:35:13
Dr. Tom O’Bryan
Cardiovascular disease or diabetes, they’re all the same. Their decades long diseases, most of them, the mechanisms are going on for decades. I’ll show you some of the science on that.
00:23:36:06 – 00:23:58:12
Nathan Crane
Now, one thing I wanted to mention there, too, which I love this I love that image as well, by the way. Yeah. Is can you go back to image really quick or it again, for those who aren’t watching, you’re only listening. I would recommend going to the YouTube. You will see this. It’s such a it’s such a great example.
00:23:58:12 – 00:24:02:23
Nathan Crane
And the problem is, I think in modern medicine.
00:24:03:02 – 00:24:03:08
Dr. Tom O’Bryan
That are.
00:24:03:13 – 00:24:04:23
Dr. Tom O’Bryan
Are are you drooling?
00:24:05:07 – 00:24:30:02
Nathan Crane
Yeah, I’m drooling. Well, it just makes you know, it makes you see or it gives a visual, I think, for a lot of people as to what the the major problem of our conventional medical approach is to these health conditions as well is they look at the immune system very often as the culprit. Right. You have an overactive immune system.
00:24:30:02 – 00:24:50:11
Nathan Crane
That’s sort of that’s how autoimmune disease is described. Your your immune system is causing the inflammation. So so we’re going to give you immunosuppressants. We’re going to suppress your immune system. We’re going to give you steroids. We’re going to give you drugs that downregulate your immune system. And in some cases, you know, some of those things and small doses might be useful for certain people.
00:24:50:11 – 00:25:11:07
Nathan Crane
But very often it is always the things on the left here that you just describe diet and lifestyle in most cases that are driving the immune system to then become overactive because it’s trying to save your life. It’s trying to save your body right. And it’s trying to save itself. And so it’s not the immune system that’s the problem.
00:25:11:07 – 00:25:12:15
Nathan Crane
It’s the diet and lifestyle.
00:25:13:01 – 00:25:19:17
Dr. Tom O’Bryan
Right. Your immune system is just trying to protect you. So the million dollar question is, what is it trying to protect you from?
00:25:20:15 – 00:25:22:05
Dr. Tom O’Bryan
That’s what you have to find out.
00:25:23:03 – 00:25:46:14
Dr. Tom O’Bryan
And for neural inflammatory diseases, the neural inflammatory state in most cases doesn’t originate in the central nervous system in the brain, the central nervous system, it’s systemic means. It’s what’s happening from the neck down that contributes to the inflammation in the brain. So if you have brain symptoms, whether it’s.
00:25:46:21 – 00:25:49:08
Dr. Tom O’Bryan
Seizures, that’s you, you know.
00:25:49:17 – 00:25:53:17
Dr. Tom O’Bryan
Children with drug resistant epilepsy, which means.
00:25:54:09 – 00:25:54:15
Dr. Tom O’Bryan
They’ve.
00:25:54:15 – 00:26:15:00
Dr. Tom O’Bryan
Tried at least three drugs and they’re not working. They then qualified for the diagnosis of drug resistant epilepsy. In the journal Gastroenterology, they published a paper that 50% of kids with drug resistant epilepsy go into complete remission on a gluten free diet.
00:26:15:00 – 00:26:15:12
Dr. Tom O’Bryan
So what?
00:26:15:22 – 00:26:16:14
Nathan Crane
That’s huge.
00:26:17:07 – 00:26:44:08
Dr. Tom O’Bryan
50%. Well, how come neurologists don’t know that? Because it’s in the gastroenterology journal and neurologists don’t read gastroenterology journals. They read neurology journals. But the problem is not in the head. That’s where the manifestation is. It’s over on that left side of those three wheels, something in lifestyle that’s activating the inflammation, that’s manifesting as seizures.
00:26:44:08 – 00:26:56:05
Nathan Crane
You’re saying drugs. You’re saying that study showed 50% of drug resistant epilepsy patients by going on a gluten free diet, were able to reverse epilepsy.
00:26:56:17 – 00:26:57:03
Dr. Tom O’Bryan
Yes.
00:26:58:05 – 00:26:59:08
Nathan Crane
That’s that’s amazing.
00:26:59:19 – 00:27:17:24
Dr. Tom O’Bryan
Yes. Yeah. This is the kind of stuff that I started reading back in the early 2000, these kind of papers that just got me so fired up to go out in the world and say, hey, we just need to learn more about wheat and about gluten and the dangers of this stuff. It was that kind of shocking information.
00:27:17:24 – 00:27:34:16
Dr. Tom O’Bryan
I mean, if you’re a parent with a child that’s got seizures, you really want to know this. You really want to know. That’s just to check. You just have to check. Is my child’s immune system fighting gluten? That’s all you have to do is check. And it’s a single simple finger prick test to find out.
00:27:35:07 – 00:27:36:06
Dr. Tom O’Bryan
Okay, let’s move on.
00:27:37:09 – 00:28:19:23
Dr. Tom O’Bryan
So if 14 of the 15 top causes of death of chronic inflammatory diseases, when do you think the chronic nature of the inflammation begins for the person diagnosed? It begins not months, years, it’s decades before the diagnosis. Growing evidence suggests that antibodies precede the onset of the symptoms of autoimmune diseases by many, many years. And depending on the disease, the biomarkers of that disease can be identified with simple testing 3 to 25 years before a diagnosis.
00:28:19:23 – 00:28:43:12
Dr. Tom O’Bryan
That’s why Nathan did the test to nip something in the bud that may occur 3 to 25 years from now is to identify the spectrum, the mechanism that’s going on. And this is the article that was game changing for us in In Functional Medicine back in 2003. This is Melissa.
00:28:43:12 – 00:28:44:05
Dr. Tom O’Bryan
Arbuckle up.
00:28:45:03 – 00:28:48:20
Dr. Tom O’Bryan
At the VA, and she published this paper in New England Journal of Medicine.
00:28:49:10 – 00:28:51:21
Dr. Tom O’Bryan
And she looked for.
00:28:51:21 – 00:28:58:08
Dr. Tom O’Bryan
People with lupus in the VA center. She was at there 132 people with lupus in that VA center.
00:28:58:20 – 00:28:59:04
Dr. Tom O’Bryan
Now.
00:28:59:19 – 00:29:20:16
Dr. Tom O’Bryan
If they’re in a VA center, they’re veterans. If they’re veterans, they were in the armed forces. If they were in the armed forces, they had their blood drawn many, many times over the years when they were healthy in the Navy or the Army or the Air Force. What most people don’t know is the government’s been saving and freezing almost all of that blood since 1978.
00:29:21:07 – 00:29:48:10
Dr. Tom O’Bryan
They’ve got tens of millions of samples of our service people’s blood. Arbuckle knew this, so she asked for permission to look at the blood of the currently diagnosed lupus patients when they were healthy in the Marines or healthy in the Navy. And she got permission. What did she find out? She found out that. And there are seven antibodies to lupus that the antibodies are present years.
00:29:48:10 – 00:30:16:18
Dr. Tom O’Bryan
They’re elevated years before there’s ever a symptom of lupus and that they follow a predictable course. And this is the graph of all seven antibodies and the horizontal zero line is normal levels, and everything above that is elevated levels. And you see that all seven antibodies elevate more each year until they hit a threshold. And here come the symptoms.
00:30:17:09 – 00:30:17:19
Dr. Tom O’Bryan
Why?
00:30:18:00 – 00:30:22:08
Dr. Tom O’Bryan
Because when you have elevated antibodies, you’re killing off more cells in your making.
00:30:23:06 – 00:30:23:22
Dr. Tom O’Bryan
Any time.
00:30:23:22 – 00:30:24:06
Dr. Tom O’Bryan
You get.
00:30:24:06 – 00:30:24:22
Dr. Tom O’Bryan
An H.
00:30:25:06 – 00:30:45:12
Dr. Tom O’Bryan
On a test meaning high, sometimes your doctor says, well, you don’t have any symptoms. Let’s just wait and see. Let’s watch this. What are they waiting for? They’re waiting for more tissue to be damaged until you get symptoms. But if it’s high or if it’s in the red zone, you’ve got a problem right now. It just hasn’t killed off so much tissue yet.
00:30:45:17 – 00:30:55:05
Dr. Tom O’Bryan
Nathan’s got a problem with his neural zoomer plus, but he’s not suffering with dementia because he’s nipping it in the bud.
00:30:55:14 – 00:31:01:01
Nathan Crane
I don’t know if I can truly testify to that. You’d have to ask my wife if that’s totally true or not.
00:31:01:01 – 00:31:02:02
Dr. Tom O’Bryan
Understand that.
00:31:02:03 – 00:31:04:01
Dr. Tom O’Bryan
When I get that, she.
00:31:04:01 – 00:31:07:12
Nathan Crane
Would probably tell you I have dementia. But actually, we better not ask her. Yeah.
00:31:08:08 – 00:31:09:16
Dr. Tom O’Bryan
Well, you know, I did a.
00:31:10:04 – 00:31:10:14
Dr. Tom O’Bryan
I did.
00:31:10:14 – 00:31:14:21
Dr. Tom O’Bryan
A telomere test recently and it came back and I was startled and I called the.
00:31:14:21 – 00:31:16:03
Dr. Tom O’Bryan
Lab and.
00:31:16:03 – 00:31:31:15
Dr. Tom O’Bryan
Talked to lab director. I said, Is this accurate? You said, Yeah, we’ve been expecting your call. We ran it twice to make sure I have the telomeres of an 11 year old. And I said, Well, my wife says, I have the emotional stability of an 11 year old. So with you.
00:31:31:15 – 00:31:31:21
Dr. Tom O’Bryan
There.
00:31:32:11 – 00:31:33:05
Nathan Crane
It makes sense.
00:31:34:00 – 00:31:34:15
Dr. Tom O’Bryan
It makes.
00:31:34:16 – 00:31:59:10
Dr. Tom O’Bryan
That right. All right. So this is our buckle. And she identified that these antibodies are elevated years beforehand. And this is the graph she did of the summary of all seven antibodies that go up every year, every year, every year. Some of those antibodies were elevated 11 years beforehand. And she made this graph up, this drawing. She said, first you have normal immunity.
00:31:59:10 – 00:32:19:17
Dr. Tom O’Bryan
That means you’ve got a normal level of antibodies to your thyroid or to your brain or to your joints or your skin. We all have some antibodies. Why? Because they’re part of the process of getting rid of the old cells, making room for the new cells called autophagy. They’re part of that process. So we all have some antibodies to our own tissue.
00:32:19:17 – 00:32:44:08
Dr. Tom O’Bryan
That’s good. But when you have elevated antibodies above the normal line, you’re killing off more cells in your making. It’s never neutral when they’re elevated. You may not have symptoms, but by definition you’re killing off more cells and you’re making. That’s why it’s elevated. So first you have the normal level, then you have benign autoimmunity, which.
00:32:44:08 – 00:32:45:24
Dr. Tom O’Bryan
Means you have.
00:32:45:24 – 00:32:58:21
Dr. Tom O’Bryan
Elevation killing off more cells in your making, but you don’t have any symptoms. Then you get symptoms that’s called pathogenic autoimmunity and then eventually you get a diagnosis. This is a beautiful graph.
00:32:59:07 – 00:33:00:00
Dr. Tom O’Bryan
To show.
00:33:00:00 – 00:33:05:19
Dr. Tom O’Bryan
The influence of genetics and our environment and how those feed the progression.
00:33:06:03 – 00:33:06:10
Dr. Tom O’Bryan
Of.
00:33:06:10 – 00:33:53:23
Dr. Tom O’Bryan
This inflammatory state. Now to increase healthy lifespan. This is where it all ties in. To increase healthy lifespan, we must address these imbalances before extensive tissue damage. That’s the key here and there is a word for it is called the prodromal or prodromal period. It means when you can identify a disease mechanism long before there is a disease is derived from the Greek word for almost which means precursor and the prodromal period in this graph that our book will put together is when it’s benign, you know, when you’re elevated, killing off more cells in your making, but you don’t really have symptoms yet.
00:33:54:13 – 00:34:05:10
Dr. Tom O’Bryan
That’s the prodromal period. And now we have really good sensitive tests that we can identify for many of these diseases, the prodromal.
00:34:05:10 – 00:34:06:01
Dr. Tom O’Bryan
Period.
00:34:06:18 – 00:34:14:07
Dr. Tom O’Bryan
Why is the neural zoomer plus such a sensitive and useful introductory test to do? Why do I do it on every.
00:34:14:07 – 00:34:14:19
Dr. Tom O’Bryan
Patient.
00:34:15:12 – 00:34:17:15
Dr. Tom O’Bryan
Is because your brain is canary in.
00:34:17:15 – 00:34:18:07
Dr. Tom O’Bryan
The coal mine.
00:34:19:03 – 00:34:46:08
Dr. Tom O’Bryan
Now a canary in a coal mine is a reference to in olden days, Thai miners coal miners would carry caged canaries down into the mines with them. And if there was any methane or carbon monoxide in the mine, the canary would die before the levels of the gas reach those that were hazardous to humans. So when the canary stopped singing, someone would go over there and see what’s going on and very drop dead.
00:34:46:08 – 00:34:55:11
Dr. Tom O’Bryan
They blow a whistle. Everyone gets out of there immediately. That’s a canary in the coal mine. Elevated antibodies are a canary in the.
00:34:55:11 – 00:34:56:04
Dr. Tom O’Bryan
Coal mine.
00:34:56:11 – 00:35:03:06
Dr. Tom O’Bryan
Of what’s going on in your body right now. That’s the way you think about elevated antibodies.
00:35:03:24 – 00:35:05:09
Dr. Tom O’Bryan
That and the.
00:35:05:09 – 00:35:26:08
Dr. Tom O’Bryan
Brain. The brain is about 2% of body weight, but it’s 80 it has 18% of the total blood volume at any one time. There’s more blood in the brain then it’s body weight. It’s saturated, it’s constantly saturated. And it’s got about 20% of the oxygen in.
00:35:26:08 – 00:35:27:21
Dr. Tom O’Bryan
Of the body at any.
00:35:27:21 – 00:35:29:19
Dr. Tom O’Bryan
One time. It’s only 2% of the weight.
00:35:30:08 – 00:35:30:17
Dr. Tom O’Bryan
And in.
00:35:30:17 – 00:35:34:23
Dr. Tom O’Bryan
Kids, it goes up to 50% of the total oxygen.
00:35:35:19 – 00:35:37:05
Dr. Tom O’Bryan
In the in the body.
00:35:37:05 – 00:36:07:02
Dr. Tom O’Bryan
That’s in the brain at any one time. Why is this important? Well, we know that the brain contains more than 10 billion in capillaries. That’s about 400 miles of blood vessels in your brain. So all that blood’s in there, traveling around, carrying oxygen, carrying nutrients to every cell in your brain because that’s your that’s your hard drive, you know, that’s the main hard drive of your computer.
00:36:07:13 – 00:36:44:00
Dr. Tom O’Bryan
And it’s just operating constantly. It’s metabolically one of the most active of all organs. So this consumption of oxygen provides the energy required for its intense activities, the most reliable data and cerebral metabolic rate. You know how your brain’s working is obtained in humans, whether you look at this. So if you have chronic systemic inflammation in your bloodstream and you don’t know because, you feel fine, where are you likely to see the first indicators of the accumulative damage of this constant inflammation.
00:36:44:00 – 00:36:45:12
Dr. Tom O’Bryan
In the body?
00:36:45:12 – 00:37:05:08
Dr. Tom O’Bryan
It just makes sense. One of the first indicators is going to be your brain, because that’s where the concentration of blood is more than anywhere else in the tissue that has the most pooling of the blood carrying these molecules of inflammation. If there’s inflammation in your bloodstream, because something about exposure and lifestyle.
00:37:05:18 – 00:37:06:04
Dr. Tom O’Bryan
And.
00:37:06:04 – 00:37:31:07
Dr. Tom O’Bryan
It’s the blood hangs out in the brain longer than anywhere else, it’s more likely to cause damage in those brain cells than anywhere else. That’s why we do the neural zoomer plus on every single patient that comes in, because it’s an excellent biomarker of early and ongoing brain damage and deterioration. There’s no other tests like it that I’ve seen.
00:37:31:23 – 00:37:32:23
Dr. Tom O’Bryan
I wish I you know.
00:37:33:09 – 00:37:35:22
Dr. Tom O’Bryan
The lab is excellent. I wish I had stock.
00:37:35:22 – 00:37:37:23
Dr. Tom O’Bryan
In the lab, but I don’t I wish I did.
00:37:38:15 – 00:37:47:23
Dr. Tom O’Bryan
Because they’re just doing such great work. So many doctors have been jumping on board, doing these kinds of tests because we get such useful information.
00:37:48:10 – 00:37:48:15
Dr. Tom O’Bryan
For.
00:37:48:15 – 00:37:49:08
Dr. Tom O’Bryan
Our patients.
00:37:49:20 – 00:37:50:04
Dr. Tom O’Bryan
Now.
00:37:50:16 – 00:37:56:08
Dr. Tom O’Bryan
Some of you remember back in 2017 the articles in the paper newspaper saying.
00:37:56:08 – 00:37:57:16
Dr. Tom O’Bryan
That Alzheimer’s.
00:37:57:16 – 00:37:59:06
Dr. Tom O’Bryan
Is going to bankrupt Medicare.
00:38:00:13 – 00:38:01:02
Dr. Tom O’Bryan
Because.
00:38:01:02 – 00:38:34:05
Dr. Tom O’Bryan
More and more people are getting Alzheimer’s. And it’s so expensive to try and take care of them. Well, the government brought a commission together of the world’s best scientists. They brought them to Washington and said, figure this out, what are we going to do? And it took them two years. And this advisory council came out with their report when they came out with their report, they included a drawing, which for me was another one of those that went on my ceiling and had me drooling.
00:38:35:02 – 00:38:48:18
Dr. Tom O’Bryan
This is the drawing from their report. Now, what’s important here to see first is the prodromal stage. Remember, we talk about prodromal stage before symptoms.
00:38:49:06 – 00:38:49:15
Dr. Tom O’Bryan
With.
00:38:49:15 – 00:38:54:09
Dr. Tom O’Bryan
Lupus that it was five, six, seven, 11 years beforehand.
00:38:54:21 – 00:38:55:05
Dr. Tom O’Bryan
Well, the.
00:38:55:05 – 00:38:59:20
Dr. Tom O’Bryan
Prodromal stage of Alzheimer’s goes on for over 20.
00:39:00:02 – 00:39:00:20
Dr. Tom O’Bryan
Years.
00:39:01:14 – 00:39:12:21
Dr. Tom O’Bryan
And there’s no symptoms. You feel fine. Now, this is the world’s best scientists trying to figure out how to avoid bankrupting Medicare.
00:39:12:21 – 00:39:13:04
Dr. Tom O’Bryan
Right.
00:39:14:23 – 00:39:35:10
Dr. Tom O’Bryan
And then after 20 plus years, you go to mild cognitive impairment. What’s that? That’s when you walk out the parking lot. See? Now, where did I park my car? I don’t remember what row I parked my car in or where did I put my keys? Or what’s the name of that person that’s walking towards me? I know them.
00:39:35:11 – 00:39:59:17
Dr. Tom O’Bryan
Come out. What’s your name? What’s your name? That’s mild cognitive impairment. Short term memory loss. Oh, I’m just stressed. I’m getting dull. Your brain cells are being killed off. That’s what’s going on. So you’ve got 25 to 30 years of this inflammation. Killing off brain cells, killing off brain cells, killing off brain cells.
00:39:59:24 – 00:40:01:14
Dr. Tom O’Bryan
Before you.
00:40:01:14 – 00:40:17:07
Dr. Tom O’Bryan
Ever get a diagnosis of Alzheimer’s. And then it just progresses from there. That’s why the neural zoomer plus is such an excellent biomarker. You identify these antibodies early that are elevated.
00:40:17:19 – 00:40:18:04
Dr. Tom O’Bryan
Now.
00:40:19:03 – 00:40:25:20
Dr. Tom O’Bryan
Nathan had a lot of them in the Green Zone, which means their normal amount of antibodies. They’re great, glad to see it.
00:40:26:05 – 00:40:26:17
Dr. Tom O’Bryan
And.
00:40:26:17 – 00:40:51:21
Dr. Tom O’Bryan
More. His test is one of the better tests I’ve ever seen for a first test. And so kudos to you, Nathan, for all that you’ve done in the past. Now here is that prodromal period in our Buckles article, and it’s the same thing before there are ever symptoms. And here is the prodromal period in the brain report in the Alzheimer’s Commission article.
00:40:52:02 – 00:40:52:20
Dr. Tom O’Bryan
Same thing.
00:40:53:05 – 00:40:53:22
Dr. Tom O’Bryan
Before there.
00:40:53:22 – 00:41:00:19
Dr. Tom O’Bryan
Are symptoms. The scientists are trying to tell us that there is this window of opportunity.
00:41:01:07 – 00:41:01:13
Dr. Tom O’Bryan
To.
00:41:01:13 – 00:41:02:16
Dr. Tom O’Bryan
Address this stuff.
00:41:03:00 – 00:41:03:23
Dr. Tom O’Bryan
Before.
00:41:03:23 – 00:41:07:14
Dr. Tom O’Bryan
You kill off so much tissue that is really, really.
00:41:07:14 – 00:41:08:24
Dr. Tom O’Bryan
Difficult to.
00:41:08:24 – 00:41:40:20
Dr. Tom O’Bryan
Arrest and reverse it. Individuals where it rise to developing an autoimmune disease should be advised to refrain from the activities and lifestyle which endangers their health and quality of life. That’s everything on that left side of the wheel, those categories on the left side. That’s why that map goes on your refrigerator, because you keep looking at that, saying, Oh, you know, I’m not really thought too much about sleep and maybe I need a little attention on sleep or about exercise or whatever it should be.
00:41:40:20 – 00:41:42:23
Dr. Tom O’Bryan
But that that map just reminds.
00:41:42:23 – 00:41:43:24
Dr. Tom O’Bryan
You of the.
00:41:43:24 – 00:41:45:24
Dr. Tom O’Bryan
Categories that you want to.
00:41:45:24 – 00:41:49:08
Dr. Tom O’Bryan
Look at. And we know now.
00:41:49:13 – 00:42:15:20
Dr. Tom O’Bryan
There have been so many studies on this. We know our buckle started it in 2003. But we now know if you have any of the antibodies to lupus, it’s 94 to 100% positive predictive value. You get lupus within 7 to 10 years. Scleroderma here is the antibodies within 11 years it’s 100%. And there is rheumatoid angiograms and primary antiphospholipid syndrome.
00:42:16:10 – 00:42:48:18
Dr. Tom O’Bryan
Now primary antiphospholipid syndrome. There are three antibodies and one of them anti beta two. Glycoprotein one is the antibody that is often responsible for unexplained miscarriages. It’s an autoimmune mechanism forming clots that go into the placental artery. And so the women will have a miscarriage. Nobody checks for these antibodies because a patient doesn’t have the symptoms of primary antiphospholipid syndrome when they’re 25 or 30 years old.
00:42:48:18 – 00:42:54:24
Dr. Tom O’Bryan
It’ll take 11 years after the antibodies are elevated before they would have the disease.
00:42:55:08 – 00:42:56:14
Dr. Tom O’Bryan
But in the meantime.
00:42:56:19 – 00:43:28:12
Dr. Tom O’Bryan
This may be and I’ve had a couple of patients where this was the mechanism for recurrent miscarriages and we identified it. And then they had healthy pregnancies and healthy babies. Hashimoto’s thyroid disease at 7 to 10 years, primarily cirrhosis 25 years, diabetes 14 years. Addison’s Chrome’s colitis, celiac. You see that the science is really clear now when you’ve got these elevated antibodies, you’ve got a problem, you’ve got a huge problem.
00:43:29:00 – 00:43:43:16
Dr. Tom O’Bryan
So this was the prodromal stage of brain deterioration. This was the one that I showed you that was so jaw dropping at 20 years. This is why we do the neural zoomer plus.
00:43:45:10 – 00:43:45:15
Dr. Tom O’Bryan
On.
00:43:45:15 – 00:43:50:03
Dr. Tom O’Bryan
Every patient that comes in. Because it’s the earliest biomarker that I know of.
00:43:50:13 – 00:43:51:07
Dr. Tom O’Bryan
Of tissue.
00:43:51:07 – 00:44:09:06
Dr. Tom O’Bryan
Damage systemically from chronic inflammation. And now let’s go to Nathan’s test. This is Nathan’s test results. And you see in the green category, they’re the majority of these antibodies.
00:44:09:11 – 00:44:09:21
Dr. Tom O’Bryan
Are.
00:44:09:21 – 00:44:28:05
Dr. Tom O’Bryan
In the green category. I mean, he’s making some, but it’s the right amount just to make new cells, get rid of the old and damaged cells, make new cells. But he’s got a couple of categories. We’re going to talk about the way you look at these in general, because there’s 53 markers here.
00:44:28:13 – 00:44:29:12
Dr. Tom O’Bryan
And it can be.
00:44:30:04 – 00:44:35:00
Dr. Tom O’Bryan
Mind boggling to try to interpret these until you had put some time.
00:44:35:00 – 00:44:35:11
Dr. Tom O’Bryan
Into it.
00:44:36:00 – 00:44:45:11
Dr. Tom O’Bryan
So you look at it in categories. The first category is brain autoimmunity and there he’s got.
00:44:45:12 – 00:44:46:09
Dr. Tom O’Bryan
Five.
00:44:47:04 – 00:44:51:14
Dr. Tom O’Bryan
Antibodies. I don’t know why that disappeared. Let me back that up again and see.
00:44:51:14 – 00:44:53:11
Dr. Tom O’Bryan
If I can get that to state. No, I.
00:44:53:11 – 00:44:54:22
Dr. Tom O’Bryan
Can’t get it to stay.
00:44:55:20 – 00:44:56:16
Dr. Tom O’Bryan
Okay.
00:44:56:16 – 00:45:22:11
Dr. Tom O’Bryan
There are five antibodies elevated in the brain autoimmunity category. So what is fueling that? A few of them we know really clearly what is most often the complication. So when you can’t digest gluten completely and no human can, those partially digested peptides can be mistaken by the immune system as a harmful component of a.
00:45:22:11 – 00:45:22:22
Dr. Tom O’Bryan
Bug.
00:45:23:15 – 00:45:34:12
Dr. Tom O’Bryan
Or of a virus. And if the immune system thinks it’s looking at a bug in your gut, it’s going to activate inflammation to kill the bug.
00:45:35:08 – 00:45:35:19
Dr. Tom O’Bryan
And that’s.
00:45:35:19 – 00:45:40:11
Dr. Tom O’Bryan
What we aren’t talking gluten today, but this is one that’s really important.
00:45:40:11 – 00:45:42:13
Dr. Tom O’Bryan
To know about.
00:45:42:14 – 00:45:47:16
Dr. Tom O’Bryan
Because these undigested food molecules can cause a.
00:45:47:16 – 00:45:49:02
Dr. Tom O’Bryan
Leak of the blood.
00:45:49:02 – 00:45:50:01
Dr. Tom O’Bryan
Brain barrier.
00:45:50:12 – 00:45:52:02
Dr. Tom O’Bryan
Which is you’ve.
00:45:52:02 – 00:46:14:13
Dr. Tom O’Bryan
Heard of leaky gut. This is leaky brain. And what happens is that for many, many people, when they get these undigested gluten fragments, they cause a breach of the blood brain barrier, leaky brain. And when you get leaky brain, you get lots of inflammation in your brain. That’s the brain.
00:46:14:13 – 00:46:18:10
Dr. Tom O’Bryan
Autoimmunity that we’re talking about here.
00:46:18:23 – 00:46:19:21
Dr. Tom O’Bryan
For example.
00:46:19:21 – 00:46:41:01
Nathan Crane
So gluten does the same thing in the brain as it does to the intestinal lining where it will actually can tear open a little, basically allow the gluten proteins to slip through into the bloodstream out of the digestive tract. That’s right. That’s exactly right. Does the same thing in the brain, though. And how does it do it in the brain?
00:46:41:01 – 00:46:45:11
Nathan Crane
Is it because it’s gone into the bloodstream and now it’s going into the brain and doing some of the.
00:46:45:11 – 00:47:02:18
Dr. Tom O’Bryan
Things that happens with gluten coming out of the stomach into the small intestine. You activate the sentry standing guard there that’s watching everything that’s coming out of the stomach, every morsel. Why? Because our ancestors, our number one concern was finding food.
00:47:03:04 – 00:47:06:17
Dr. Tom O’Bryan
You know, we’ve only been farmers.
00:47:06:17 – 00:47:26:05
Dr. Tom O’Bryan
And agriculture for 10,000 years. Before that, we were nomads. We followed the herbs. Means you’re walking every day, or you’re walking regularly and you’re looking for food. That was the number one thing. And they often eat food that had bad bugs on it. And if they didn’t have a good defense mechanism against the bad bugs, they.
00:47:26:05 – 00:47:26:16
Dr. Tom O’Bryan
Died.
00:47:27:06 – 00:47:38:06
Dr. Tom O’Bryan
And they didn’t reproduce. So there was no offspring from them. But if they had a good defense mechanism, sentry standing guard inside the gut that whenever a bug.
00:47:38:06 – 00:47:40:06
Dr. Tom O’Bryan
Came down with the food, you.
00:47:40:06 – 00:47:42:20
Dr. Tom O’Bryan
Activate the immune system to kill the.
00:47:42:20 – 00:47:43:04
Dr. Tom O’Bryan
Bug.
00:47:44:04 – 00:48:04:07
Dr. Tom O’Bryan
Then you survived. And for all of us here today, that’s our ancestors. So we all have this this survival mechanism, every single one of us that is called toll like receptor four. It’s a century, I think, of the soldiers at Buckingham Palace with those big hands.
00:48:04:07 – 00:48:09:00
Dr. Tom O’Bryan
You know, they’re dormant. They don’t do anything. But don’t mess with those guys.
00:48:09:08 – 00:48:24:17
Dr. Tom O’Bryan
Do not mess with those guys. Right. So that if they see something, if they see a bug, they destroy. They do two things. First, they send a message to increases annually. Zombieland opens up the tight junctions. Now here comes leaky gut.
00:48:25:01 – 00:48:25:14
Dr. Tom O’Bryan
Why?
00:48:25:19 – 00:48:30:23
Dr. Tom O’Bryan
Because when you have a leaky gut, water comes from your body into the.
00:48:30:23 – 00:48:33:24
Dr. Tom O’Bryan
Gut to wash the bug with the poop.
00:48:34:20 – 00:48:48:21
Dr. Tom O’Bryan
Leaky gut is not bad for you. Leaky gut saves your life every single day. Excessive leaky gut is bad for you. So that’s the first thing that the toll like receptor does is it activates Xinyu Lin so you.
00:48:48:21 – 00:48:51:01
Dr. Tom O’Bryan
Get leaky gut well.
00:48:51:10 – 00:49:23:09
Dr. Tom O’Bryan
Those design you lin proteins are also in the lining of the blood brain barrier and you’ve got toll like receptor there also. And the same thing it sees these gluten molecules, it activates them and you also inulin increase your inulin you open up the blood brain barrier. It’s the same mechanism. And at Harvard, what they teach and this is the exact quote, cause I’ve said it so often, gluten is misinterpreted as a harmful component of a microorganism.
00:49:24:11 – 00:49:42:08
Dr. Tom O’Bryan
The amino acid structure of these poorly digested components of wheat look like the outer shell of a bug, and so your immune system is going to fight it every single time it sees it, without exception. And this happens to every human.
00:49:42:17 – 00:49:55:17
Nathan Crane
Now, what about people who go, I’m sure you’ve heard this. I hear this from clients and patients and people all the time is, Oh, I can’t eat gluten here, but I go to Europe and I can eat, you know, all the bread and pasta and I don’t have any issues.
00:49:56:04 – 00:50:02:15
Dr. Tom O’Bryan
Yeah, that’s that’s actually not the case. So gluten activates the immune system to.
00:50:02:15 – 00:50:03:24
Dr. Tom O’Bryan
Fight to fight it.
00:50:04:11 – 00:50:06:16
Dr. Tom O’Bryan
It’s other components of wheat called.
00:50:06:16 – 00:50:07:14
Dr. Tom O’Bryan
Fodmaps.
00:50:08:00 – 00:50:11:24
Dr. Tom O’Bryan
That cause the bloating in the gas in the abdominal cramps and all of.
00:50:11:24 – 00:50:13:17
Dr. Tom O’Bryan
That and the gluten.
00:50:14:03 – 00:50:43:19
Dr. Tom O’Bryan
The wheat in Europe is lower in fodmaps, so there’s less gut symptoms. So people feel when they go there, but they still activate the immune system. They still get all of the inflammatory. Like in your case, you’ve got elevated antibodies to breaking cells. And as this slide shows, when you have antibodies to gluten, they can cross react is called molecular mimicry and they can attack your Pekingese cells.
00:50:43:19 – 00:51:08:19
Dr. Tom O’Bryan
Those antibodies to gluten will attack that component of your brain called per kanji cells. So you get all this inflammation in your brain from the antibodies to gluten. Then your body makes more antibodies to kanji cells to get rid of the old and damaged Perkins cells. And so you get more elevation of Perkins cells, and here comes the inflammatory cascade in your brain.
00:51:09:13 – 00:51:11:16
Dr. Tom O’Bryan
The same thing occurs.
00:51:11:21 – 00:51:13:05
Dr. Tom O’Bryan
With a.
00:51:13:17 – 00:51:15:12
Dr. Tom O’Bryan
Cerebellum in your brain.
00:51:16:07 – 00:51:17:16
Dr. Tom O’Bryan
That the.
00:51:18:12 – 00:51:42:23
Dr. Tom O’Bryan
Gluten protein called Gladden and also the proteins in milk called Butyrate fillings will cross react with the cerebellum in your brain. In our practice, 26% of everyone that has elevated antibodies to gluten also has elevated antibodies to cerebellum. 26% of.
00:51:42:23 – 00:51:43:02
Dr. Tom O’Bryan
That.
00:51:43:14 – 00:51:57:00
Dr. Tom O’Bryan
Means killing off brain cells, killing off brain cells, killing off brain cells. This is why people in their seventies can’t run up and down stairs is because they’ve lost so many cerebellar cells. It’s hard to keep their balance.
00:51:59:00 – 00:52:01:00
Dr. Tom O’Bryan
But in many people.
00:52:01:03 – 00:52:20:22
Dr. Tom O’Bryan
And it’s called gluten ataxia when it gets really bad. But for many people, it’s because of a sensitivity to wheat that didn’t give them gut pain, so they didn’t pay attention to it. Next one for you. After the brain autoimmunity is infections.
00:52:21:11 – 00:52:22:14
Dr. Tom O’Bryan
And you.
00:52:22:14 – 00:52:30:24
Dr. Tom O’Bryan
Have seven different antibodies elevated to infections. And these are strongly associated.
00:52:31:06 – 00:52:33:19
Dr. Tom O’Bryan
With the.
00:52:36:00 – 00:52:38:19
Dr. Tom O’Bryan
Deposit of beta beta amyloid.
00:52:39:06 – 00:52:39:14
Dr. Tom O’Bryan
And.
00:52:39:14 – 00:52:51:13
Dr. Tom O’Bryan
Tau proteins. So when you’re at when you’re when your brain is fighting cytomegalovirus, Epstein-Barr Streptococcus bacteria.
00:52:52:18 – 00:52:54:00
Dr. Tom O’Bryan
The the.
00:52:54:00 – 00:52:57:04
Dr. Tom O’Bryan
Amount of inflammation in your brain is quite.
00:52:57:04 – 00:52:57:12
Dr. Tom O’Bryan
High.
00:52:58:09 – 00:52:59:23
Dr. Tom O’Bryan
So this is an area that.
00:53:00:06 – 00:53:00:12
Dr. Tom O’Bryan
Would.
00:53:00:12 – 00:53:22:13
Dr. Tom O’Bryan
Be good to spend maybe six months to a year building your immune system, to go after viruses, to really focus on that more than you may have in the past. Now, this could have been a lot worse in the past. It could have been. There’s six more different infections that are tested for, and you didn’t have any of those.
00:53:22:24 – 00:53:30:04
Dr. Tom O’Bryan
So it could have been much worse than it is now. But this just suggests putting some attention.
00:53:30:12 – 00:53:30:24
Dr. Tom O’Bryan
On.
00:53:30:24 – 00:53:35:13
Dr. Tom O’Bryan
Enhancing or strengthening your immune response against viruses.
00:53:36:09 – 00:54:02:20
Nathan Crane
Now, these are and these are viruses most people have, have or have had at some point in their life. Right. We’re looking at Epstein-Barr to look for people who can’t see looking at streptococcal a most of these are so there’s Epstein-Barr, Epstein-Barr, cytomegalovirus, cytomegalovirus, Epstein-Barr virus streptococcal a so, so. So I’ve seen bar that it shows like three or four times.
00:54:03:01 – 00:54:09:15
Nathan Crane
Those are just different antibodies for it or different antigens, for example. Is that what they are?
00:54:09:15 – 00:54:15:00
Dr. Tom O’Bryan
Those are different components of the Epstein-Barr virus that your immune system’s going after.
00:54:15:13 – 00:54:33:19
Nathan Crane
Okay, so it’s showing like so it shows one, two, three, four. So I’ve seen bar shows up four times, so it’s very likely, right? Yes. And inside of them, cytomegalovirus shows up twice. And then streptococcal A shows up. And then what are the other one? Is this.
00:54:34:20 – 00:54:42:07
Dr. Tom O’Bryan
Streptococcus is a bacteria notorious in the oral.
00:54:42:08 – 00:54:44:02
Dr. Tom O’Bryan
Microbiome. Mm hmm.
00:54:44:03 – 00:54:59:16
Dr. Tom O’Bryan
So this this is a case where I would be changing the person’s toothpaste. I’d be giving them more oral care, more focus on creating a healthier, diverse microbiome in your mouth. You we swallow a liter, a.
00:54:59:16 – 00:55:03:13
Dr. Tom O’Bryan
Day of saliva, of adults.
00:55:03:13 – 00:55:04:11
Dr. Tom O’Bryan
A liter.
00:55:04:11 – 00:55:06:21
Dr. Tom O’Bryan
A day. And if.
00:55:06:21 – 00:55:09:13
Dr. Tom O’Bryan
Your oral microbiomes out of balance, if.
00:55:09:13 – 00:55:10:14
Dr. Tom O’Bryan
You if.
00:55:10:14 – 00:55:15:01
Dr. Tom O’Bryan
You get pink water when you brush your teeth because you get a little bit of blood in the water, things like that.
00:55:16:05 – 00:55:18:12
Dr. Tom O’Bryan
You’ve got gingivitis and.
00:55:18:12 – 00:55:24:14
Dr. Tom O’Bryan
That’s leaky gums. And that’s the only reason that I know as to why dentists.
00:55:25:00 – 00:55:25:16
Dr. Tom O’Bryan
Give.
00:55:25:16 – 00:55:39:06
Dr. Tom O’Bryan
Antibiotics before they work in your mouth. Because we know when they work in your mouth, they sport some water in there. You spit it out and it’s red with blood. They gave you leaky gums and it takes three or four days for the leaky gums to heal.
00:55:39:20 – 00:55:40:04
Dr. Tom O’Bryan
So in the.
00:55:40:04 – 00:55:43:07
Dr. Tom O’Bryan
Meantime, if you’ve got strep in your mouth.
00:55:43:13 – 00:55:43:17
Dr. Tom O’Bryan
You.
00:55:43:17 – 00:56:04:06
Dr. Tom O’Bryan
Have a history of strep infections in your life and you’ve never really done an oral microbiome rebuilding program. So you likely have high dose, high amounts of strep. Then the strep can go through the leaky gums into the bloodstream, and if it goes through the leaky gums into the bloodstream, it can set up shop anywhere in your body and start to colonize.
00:56:04:18 – 00:56:28:14
Dr. Tom O’Bryan
And when it starts to colonize, now your immune system recognizes it and says, Whoa, I better fight this, and you make antibodies to strep like you’ve got here. Well, the antibodies to strep in your bloodstream trying to kill strep everywhere it finds it. But strep has a molecular mimicry with the balance of your heart and the antibody is will attack the valves of your heart.
00:56:28:14 – 00:56:31:08
Dr. Tom O’Bryan
That’s rheumatic fever and that’ll kill you.
00:56:32:10 – 00:56:52:23
Dr. Tom O’Bryan
So to prevent that, dentists give antibiotics. So they’re in bloodstream. So any little strep bacteria from your mouth that gets through the leaky gums into the bloodstream gets killed right away. It doesn’t have a chance to colonize. That’s why they give you antibiotics. It’s a shotgun approach to protect you against something.
00:56:53:07 – 00:56:57:00
Dr. Tom O’Bryan
That you may or may not get. Yeah.
00:56:57:12 – 00:57:03:21
Nathan Crane
Makes sense. But all the other consequences that come with antibiotics, often, in my opinion, are not worth it.
00:57:04:04 – 00:57:06:23
Dr. Tom O’Bryan
Exactly.
00:57:06:23 – 00:57:07:08
Dr. Tom O’Bryan
Now.
00:57:08:05 – 00:57:23:06
Dr. Tom O’Bryan
You did not have antibodies elevated to herpes. That was in the green category three, which is great, but this is a little bonus for people because so many people get cold sores. So many people have herpes virus.
00:57:24:05 – 00:57:25:08
Dr. Tom O’Bryan
When testing for it.
00:57:26:01 – 00:57:35:14
Dr. Tom O’Bryan
Somewhere around in my practice, 60% of everyone I test will have elevated antibodies to herpes. So I wanted to give everyone.
00:57:36:01 – 00:57:38:04
Dr. Tom O’Bryan
An appreciation for.
00:57:38:04 – 00:57:39:20
Dr. Tom O’Bryan
What happens when.
00:57:39:21 – 00:57:40:13
Dr. Tom O’Bryan
You have.
00:57:40:23 – 00:57:54:00
Dr. Tom O’Bryan
Herpes. And so these these researchers, they were so clear, they said we are researchers and clinicians working on Alzheimer’s disease or related topics and we write to express our concern.
00:57:54:08 – 00:57:54:15
Dr. Tom O’Bryan
That.
00:57:54:15 – 00:58:01:06
Dr. Tom O’Bryan
One particular aspect of the disease has been neglected, even though treatment based on it might slow.
00:58:01:11 – 00:58:01:19
Dr. Tom O’Bryan
Or.
00:58:01:19 – 00:58:21:11
Dr. Tom O’Bryan
Arrest Alzheimer’s progression. We refer to the many studies mainly on humans implicating specific microbes in the elderly brain, notably herpes simplex one chlamydia, pneumonia and several types of skyrockets in the etiology of Alzheimer’s, meaning the.
00:58:21:15 – 00:58:23:04
Dr. Tom O’Bryan
Development of.
00:58:23:04 – 00:58:53:07
Dr. Tom O’Bryan
Alzheimer’s. The first observations of herpes simplex one in Alzheimer’s brain were reported almost three decades ago and there’s currently 248 studies on herpes simplex one and Alzheimer’s. So these cold sores that we get that usually take a week or two to go away. That’s a herpes virus, often Alzheimer’s associated with neuronal loss, progressive synaptic dysfunction.
00:58:53:16 – 00:58:54:07
Dr. Tom O’Bryan
Accompanied.
00:58:54:07 – 00:58:56:10
Dr. Tom O’Bryan
By the deposition of amyloid beta.
00:58:56:10 – 00:58:59:10
Dr. Tom O’Bryan
Peptide and their.
00:58:59:10 – 00:59:14:19
Dr. Tom O’Bryan
Diagnostic criteria for the disease. These constitute the hallmarks of Alzheimer’s. But whether there are causes of Alzheimer’s or consequences is unknown. We suggest that these are indicators of an infectious etiology.
00:59:15:07 – 00:59:15:21
Dr. Tom O’Bryan
And I’m not going.
00:59:15:21 – 00:59:17:15
Dr. Tom O’Bryan
To go I’ve got a bunch of studies that.
00:59:17:15 – 00:59:18:21
Dr. Tom O’Bryan
Show beta.
00:59:18:21 – 00:59:23:19
Dr. Tom O’Bryan
Amyloid plaque is an immune response to microbes in the.
00:59:23:19 – 00:59:24:03
Dr. Tom O’Bryan
Brain.
00:59:24:21 – 00:59:26:22
Dr. Tom O’Bryan
It’s your immune system trying to protect.
00:59:26:22 – 00:59:27:02
Dr. Tom O’Bryan
You.
00:59:27:13 – 00:59:29:22
Dr. Tom O’Bryan
Mostly from something called LPs.
00:59:30:10 – 00:59:34:02
Dr. Tom O’Bryan
Which maybe we’ll do another show on another time.
00:59:34:11 – 00:59:39:18
Dr. Tom O’Bryan
But it’s an immune response, trying to protect you that produces this beta amyloid.
00:59:39:18 – 00:59:40:06
Dr. Tom O’Bryan
Plaque.
00:59:41:06 – 01:00:12:12
Dr. Tom O’Bryan
And these these researchers are saying we’ve got a huge problem here. Microbes can cause chronic as well as acute diseases. Some microbes can remain latent in the body with the potential for reactivation, the effects of which might occur years after initial infection. Evidence for an infectious immune component is huge. With Alzheimer’s, then they go through. There are six reasons as to why they’re concerned about this.
01:00:12:12 – 01:00:45:24
Dr. Tom O’Bryan
Viruses and other microbes are present in the brain of most elderly people. Although they’re usually dormant. Reactivation can occur after stress or immunosuppression. For example, herpes DNA is amplified in the brain of immunosuppressed patients. So when you take medication to suppress your immune system, these viruses can run rampant. Herpes produces damage in localized areas of the central nervous system, which are associated with memory, cognitive function.
01:00:46:11 – 01:00:47:00
Dr. Tom O’Bryan
And.
01:00:47:00 – 01:00:55:16
Dr. Tom O’Bryan
Affective processes as well as personality in the brain of Alzheimer’s patients. Pathogen signatures of herpes simplex one.
01:00:56:01 – 01:00:56:16
Dr. Tom O’Bryan
Call.
01:00:56:16 – 01:01:47:02
Dr. Tom O’Bryan
Localize meaning they’re right there with the Alzheimer’s pathology. They’re right there. Herpes infection, as revealed by positive blood tests, is significantly associated with the development of Alzheimer’s. Alzheimer’s has long been known to have a prominent inflammatory component characteristic of infections. And for those that have the apple, e.g. gene, making them even more vulnerable to Alzheimer’s, when you have these infections, it’s made worse features of Alzheimer’s pathology are transmissible by inoculation of an Alzheimer’s brain to primates in mice, meaning you take a little piece of the brain tissue of an Alzheimer’s patient, which is loaded with viruses, and you put it in a in an animal.
01:01:47:10 – 01:02:09:12
Dr. Tom O’Bryan
They get Alzheimer’s. So the next category after brain autoimmunity is brain inflammation. And these markers here that you have are with anti dopamine receptors. Dopamine is a hormone. We make.
01:02:09:22 – 01:02:10:11
Dr. Tom O’Bryan
And.
01:02:10:11 – 01:02:12:13
Dr. Tom O’Bryan
Is the lack of dopamine.
01:02:13:20 – 01:02:14:09
Dr. Tom O’Bryan
That.
01:02:14:09 – 01:02:58:03
Dr. Tom O’Bryan
Is responsible for the development of Parkinson’s disease. And so these indicators of inflammation are directed towards nuclear components in the blood from patients with affective disorder. I’m going to show you a couple of studies that show this is odd suicide and people that have these antibodies elevated. The far end of that spectrum is on suicides. And they looked at patients with 13 excuse me, 16 patients with major depressive disorder, 13 with dysthymia, those ten with substance abuse disorders, eight with adjustment disorders, meaning.
01:02:58:03 – 01:02:59:19
Dr. Tom O’Bryan
They didn’t cope with life very well.
01:03:00:06 – 01:03:13:17
Dr. Tom O’Bryan
Six With panic or anxiety disorders. Two Schizophrenic disorders, one schizophrenic, and five with other axis one disorder. So they looked at all these different categories.
01:03:14:03 – 01:03:15:03
Dr. Tom O’Bryan
Of cognitive.
01:03:15:03 – 01:03:16:14
Dr. Tom O’Bryan
And brain dysfunction.
01:03:16:22 – 01:03:19:20
Dr. Tom O’Bryan
And what did they find? The patient groups.
01:03:19:20 – 01:03:52:07
Dr. Tom O’Bryan
Showed a much higher titer of dopamine antibodies compared to the control group. And when you look at the graph, this is an O-M-G of those that had the elevated antibodies are above the dotted line, the horizontal dotted line. These are the ones that attempted suicide. Almost all of them had elevated antibodies to dopamine receptors, which means when people have these markers elevated, some will have one.
01:03:52:20 – 01:04:15:18
Dr. Tom O’Bryan
Oh, I guess maybe 40% of them that I’ve seen will have both of them elevated. They’re more susceptible to anxiety, depression, schizophrenic tendencies, severe depression. And you know, Nathan, given the lifestyle you live, it’s really kudos to you.
01:04:16:05 – 01:04:16:17
Dr. Tom O’Bryan
That.
01:04:16:21 – 01:04:20:00
Dr. Tom O’Bryan
You know, you’re stable, healthy life, healthy family.
01:04:21:18 – 01:04:24:18
Dr. Tom O’Bryan
If you had been throwing.
01:04:24:18 – 01:04:28:01
Dr. Tom O’Bryan
Gasoline on the fire with an inflammatory lifestyle.
01:04:28:09 – 01:04:29:01
Dr. Tom O’Bryan
You would.
01:04:29:01 – 01:04:34:03
Dr. Tom O’Bryan
Probably be more vulnerable to your brain out working as well as it’s working right.
01:04:34:03 – 01:04:34:10
Dr. Tom O’Bryan
Now.
01:04:35:02 – 01:04:56:17
Nathan Crane
Hmm. Yeah, that’s really interesting. And this is definitely a big eye opener for people, for sure. Yeah. Yeah. I mean, so you see these, you know, markers and then to know I think there’s a lot to do with, you know, aside from diet and and, you know, toxins and different things, foods and so forth, they can contribute to all this.
01:04:57:09 – 01:05:41:21
Nathan Crane
You know, I have a deep spiritual practice in my life and I meditate daily and I have, you know, a very feel like a very purposeful life. So I’m, you know, every day I’m very peaceful, very happy in my life. And so to know that if I didn’t have those practices and and if I let’s say I was eating a really inflammatory diet and was really I’d say living a kind of a standard American way of living very stressed, you know, not much spiritual purpose, not much purpose in life, not much happiness on a daily basis, stressed out all day, and all the toxins and food and chemicals and drinks that are, you know, cigarets
01:05:41:21 – 01:06:00:21
Nathan Crane
and alcohol and all these things that are going in people’s body every single day. No wonder so many millions and millions of people are depressed and right, idle and hating life and just have no real to feel like they don’t have anything to really live for. They live because they live, but they don’t feel like they have anything to live for.
01:06:01:07 – 01:06:01:23
Dr. Tom O’Bryan
Right? Right.
01:06:02:11 – 01:06:12:00
Nathan Crane
Exactly right. And that’s how when I was a teenager, I was that way because that’s exactly how I was. And I was suicidal and because I had nothing to live for, you know?
01:06:12:00 – 01:06:15:00
Dr. Tom O’Bryan
Kudos to you, man. Cool. Really kudos that.
01:06:15:00 – 01:06:16:04
Dr. Tom O’Bryan
You you.
01:06:16:05 – 01:06:17:19
Dr. Tom O’Bryan
Developed the disciplines.
01:06:18:03 – 01:06:26:01
Dr. Tom O’Bryan
To engage with your life in a healthy way. Really kudos on.
01:06:26:01 – 01:06:34:24
Dr. Tom O’Bryan
That. Now, is there any family history of cognitive decline or anxiety, depression, those types of things?
01:06:34:24 – 01:06:39:06
Nathan Crane
Yeah. Um, yeah, definitely.
01:06:39:06 – 01:06:44:17
Dr. Tom O’Bryan
All right. So so then you probably carry carry some genes that made that one of the weak links in your chain.
01:06:45:09 – 01:06:47:01
Dr. Tom O’Bryan
You know, if you pull a chain that.
01:06:47:01 – 01:07:08:07
Dr. Tom O’Bryan
Always breaks it, the weakest link, it’s the one in the middle. The other energy, heart, your brain, your liver web, your genetic weak link is if you pull it the chain and the pull on the chain is inflammation. That’s the pull on the chain. So reduce your inflammatory re triggers, reduce your inflammation, and the chain doesn’t break.
01:07:10:06 – 01:07:10:19
Dr. Tom O’Bryan
In the school.
01:07:10:20 – 01:07:27:01
Dr. Tom O’Bryan
But next category, there’s one here specific. Well, there’s actually two for food, but I’ve already done the gluten ones are cerebellum and frickin g cells. This one is called Aqua PA. And for.
01:07:27:14 – 01:07:27:24
Dr. Tom O’Bryan
Now when.
01:07:27:24 – 01:07:34:01
Dr. Tom O’Bryan
You have elevated antibodies to aqua porn for it’s a breach of the blood brain barrier, it’s a leaky.
01:07:34:01 – 01:07:37:05
Dr. Tom O’Bryan
Brain and it’s.
01:07:37:05 – 01:07:37:22
Dr. Tom O’Bryan
Commonly.
01:07:37:22 – 01:07:39:24
Dr. Tom O’Bryan
Associated with vision.
01:07:39:24 – 01:07:42:19
Dr. Tom O’Bryan
Disturbances after enough.
01:07:43:02 – 01:07:44:01
Dr. Tom O’Bryan
Tissue damage.
01:07:44:01 – 01:07:55:17
Dr. Tom O’Bryan
Has occurred. And the association of this one was is with me also. And they found that most patients.
01:07:55:17 – 01:07:56:01
Dr. Tom O’Bryan
With.
01:07:57:04 – 01:08:38:17
Dr. Tom O’Bryan
Relapsing remitting multiple sclerosis had elevated antibodies to aqua porn four and they also had elevated antibodies to the aqua porn for in for foods. And I love this graph because the darker the red, the more likely it’s happening. So as you can see, aqua portions are a family of cells that are in your nervous system. And in some foods, same cells and in soy, for example, if you have if you have a sensitivity to soy, you’ve got elevated antibodies to soy.
01:08:38:17 – 01:08:42:04
Dr. Tom O’Bryan
You also are going to have elevated antibodies to.
01:08:42:22 – 01:08:43:12
Dr. Tom O’Bryan
The column.
01:08:43:12 – 01:08:50:00
Dr. Tom O’Bryan
On the right s100. BE That’s a blood brain barrier marker. Myelin basic protein.
01:08:50:07 – 01:08:51:24
Dr. Tom O’Bryan
Is one.
01:08:51:24 – 01:08:57:23
Dr. Tom O’Bryan
Of the antibodies primarily involved with mouse development, human aqua PA and for.
01:08:58:07 – 01:09:00:17
Dr. Tom O’Bryan
And myeloma oligo ganglia side.
01:09:00:17 – 01:09:19:02
Dr. Tom O’Bryan
So the correlation when someone has a coupon for antibodies elevated need to do the test for soy corn, spinach and tomatoes. It’s called the lectin zoomer and I would recommend that test to you, Nathan, because I think you’re going to.
01:09:19:02 – 01:09:20:11
Dr. Tom O’Bryan
Find that.
01:09:20:22 – 01:09:25:21
Dr. Tom O’Bryan
Maybe it’s tomatoes, maybe it’s spinach, you know, really good foods. But for your.
01:09:25:21 – 01:09:26:10
Dr. Tom O’Bryan
Body.
01:09:26:18 – 01:09:32:05
Dr. Tom O’Bryan
There is something that’s fueling this Aqua Palm for antibodies in your brain.
01:09:32:19 – 01:10:04:14
Nathan Crane
Now. Now I eat a lot of soy tomatoes and spinach. I stopped eating corn. You know, I eat all of those things organic. And the question I have about it, so so I do eat those things pretty often. But the question I have about doing some of those antibody tests is like, is it maybe you can help clear up some of the controversy around why a lot of doctors don’t do a lot of functional medical doctors don’t actually like doing those kinds of tests.
01:10:05:13 – 01:10:13:13
Nathan Crane
They say that because if you’re eating a lot of those foods anyway, you’re going to have those antibodies show up in your blood test.
01:10:13:23 – 01:10:14:19
Dr. Tom O’Bryan
Yeah, well.
01:10:15:24 – 01:10:28:10
Nathan Crane
So it doesn’t necessarily give you that you have the result of saying just because you’re eating them a lot and it shows up in your blood doesn’t necessarily give you an accurate understanding of like, is this actually doing some kind of harm to you or not? Is that true?
01:10:28:11 – 01:10:53:19
Dr. Tom O’Bryan
Show me the studies on that. There’s there is no science to that opinion that I’m aware of. And if you’ve got elevated aqua porn for antibodies, which is one of the mechanisms in development of M.S and other demyelinating diseases, you need to stop throwing gasoline on the fire. So if you have elevated antibodies to make to tomatoes, you’re done with tomatoes for at least a year.
01:10:54:03 – 01:10:56:19
Dr. Tom O’Bryan
And then you reach out and if you.
01:10:56:19 – 01:11:01:10
Dr. Tom O’Bryan
Find it’s all come down, the component for antibodies that come down, the tomato antibodies come down.
01:11:01:18 – 01:11:02:06
Dr. Tom O’Bryan
Then you have.
01:11:02:06 – 01:11:09:06
Dr. Tom O’Bryan
Tomatoes once or twice a week for a month and then check again. Can you eat them once or twice a month and not have a problem?
01:11:10:20 – 01:11:12:11
Dr. Tom O’Bryan
So you the.
01:11:12:11 – 01:11:15:09
Dr. Tom O’Bryan
Only food that is permanent as far as I.
01:11:15:09 – 01:11:15:18
Dr. Tom O’Bryan
Know.
01:11:16:07 – 01:11:29:13
Dr. Tom O’Bryan
When your immune system is fighting that food, the only one that’s permanent is wheat. There’s no exceptions. You create memory B cells to wheat, but you don’t create memory B cells to tomatoes or to.
01:11:29:13 – 01:11:30:02
Dr. Tom O’Bryan
Soy.
01:11:30:06 – 01:11:38:06
Dr. Tom O’Bryan
Or to spinach or to corn. So if you currently have antibodies to those, stop eating those foods because you’re killing off myelin.
01:11:38:06 – 01:11:40:00
Dr. Tom O’Bryan
Right now and your.
01:11:40:06 – 01:11:42:18
Dr. Tom O’Bryan
Your blood brain barrier with the aqua board forming.
01:11:42:18 – 01:11:43:10
Dr. Tom O’Bryan
Antibodies.
01:11:44:08 – 01:11:52:10
Nathan Crane
So you get so you give your body a break from it and let those antibodies come down and then and then retest and see if that’s what it was.
01:11:52:21 – 01:11:53:06
Dr. Tom O’Bryan
Yeah.
01:11:53:13 – 01:12:22:04
Dr. Tom O’Bryan
You know, and the key is the test that’s the key. And B for Vibrant came out with this technology called silicon chip technology. The tests were wrong two or three out of ten times. That’s called the sensitivity and specificity, but they were wrong on occasion. I started doing double blind tests on patients. I would take two tubes of blood out of the arm and I would label the second one.
01:12:22:14 – 01:12:32:22
Dr. Tom O’Bryan
Joe Smith and I send it to the lab. And I, you know, I have to pay for it myself, but I’m checking up on the lab and two or three out of ten times it comes back completely.
01:12:32:22 – 01:12:36:09
Dr. Tom O’Bryan
Different, not just a little bit different. Completely different.
01:12:36:24 – 01:12:48:14
Dr. Tom O’Bryan
And I lost faith in all of those lab tests when Vibrant came out in 2015 with this new technology and Mayo Clinic calls it a new era in laboratory medicine.
01:12:48:23 – 01:12:49:05
Dr. Tom O’Bryan
I mean.
01:12:49:05 – 01:12:50:21
Dr. Tom O’Bryan
Those are bold words.
01:12:51:10 – 01:12:52:22
Dr. Tom O’Bryan
You know what it is?
01:12:52:22 – 01:13:07:10
Dr. Tom O’Bryan
Because it’s 97 to 100% accurate every single time. And so and I’ve done double blinds and vibrance tests, and I’ve only done that three times. All three times. It was right on the money and I just didn’t want to spend the money anymore. The extra money.
01:13:07:17 – 01:13:12:11
Dr. Tom O’Bryan
Ordering, you know, follow up tests or piggyback.
01:13:12:11 – 01:13:13:05
Dr. Tom O’Bryan
Tests on that.
01:13:14:07 – 01:13:15:17
Dr. Tom O’Bryan
But there’s.
01:13:16:11 – 01:13:17:15
Dr. Tom O’Bryan
I have not found.
01:13:17:15 – 01:13:18:12
Dr. Tom O’Bryan
A patient yet.
01:13:19:01 – 01:13:28:14
Dr. Tom O’Bryan
Who had elevated aqua porn for antibodies, who didn’t have one or more of these four foods elevated.
01:13:28:14 – 01:13:29:01
Nathan Crane
Interesting.
01:13:29:01 – 01:13:29:09
Dr. Tom O’Bryan
And so.
01:13:29:17 – 01:13:30:19
Dr. Tom O’Bryan
There’s something in there.
01:13:31:01 – 01:13:31:19
Dr. Tom O’Bryan
And that’s.
01:13:31:19 – 01:13:34:06
Nathan Crane
A lectern. That’s the lectern. Zoomer Test.
01:13:34:06 – 01:13:53:22
Dr. Tom O’Bryan
The lectern. ZUBER That’s correct. Got It and I’m doing one more bonus for you guys. This one came back negative you the rage antibody, which is good and that’s because you eat a really clean diet.
01:13:54:08 – 01:13:55:05
Dr. Tom O’Bryan
You know. But I thought.
01:13:55:05 – 01:13:57:23
Nathan Crane
It was because I got rid of all my rage when I was a teenager.
01:13:59:04 – 01:14:12:00
Dr. Tom O’Bryan
Well, perhaps perhaps that that contributed. But rage stands for receptor of advanced GLYCATION end products and advanced GLYCATION end products.
01:14:12:09 – 01:14:14:09
Dr. Tom O’Bryan
Are what.
01:14:14:09 – 01:14:21:11
Dr. Tom O’Bryan
Happens when you cook food at a high temperature. Think of bread dough when you need bread.
01:14:21:18 – 01:14:22:22
Dr. Tom O’Bryan
If you’re kneading it.
01:14:23:19 – 01:14:33:14
Dr. Tom O’Bryan
It’s soft and kind of gooey, but you put it in the oven and now there’s a crust that’s advanced glycation end products, you change the protein and carbohydrate structure.
01:14:33:14 – 01:14:34:04
Dr. Tom O’Bryan
Of the food.
01:14:34:23 – 01:14:59:00
Dr. Tom O’Bryan
So that means barbecued food where the meats are blackened from being burnt. That’s advanced glycation end products. Any time you burn food or you deep fried food, high temperature, that’s advanced glycation end products and they bind onto the receptor for advanced glycation end products. That’s called the rage receptor.
01:14:59:23 – 01:15:00:08
Dr. Tom O’Bryan
Now.
01:15:00:19 – 01:15:24:05
Dr. Tom O’Bryan
This is really important because we’re talking about the brain here, the blood brain barrier is important for amyloid beta brain balance. And the blood brain barrier regulates the transport of amyloid beta through to receptors. One is the LDL receptor, low density lipoprotein cholesterol, the LDL receptor.
01:15:24:16 – 01:15:25:05
Dr. Tom O’Bryan
And.
01:15:25:11 – 01:15:45:23
Dr. Tom O’Bryan
The receptor for advanced glycation end products. The receptor for advanced glycation end products mediates the influx. It escorts amyloid beta into the brain, so more amyloid beta into the brain, whereas the low density lipoprotein escorts amyloid beta.
01:15:46:02 – 01:15:49:17
Dr. Tom O’Bryan
Out of the brain.
01:15:49:17 – 01:15:55:17
Dr. Tom O’Bryan
If rage expression creates an increase in the influx of amyloid beta through the blood brain barrier.
01:15:56:01 – 01:15:56:17
Dr. Tom O’Bryan
How do we.
01:15:56:17 – 01:16:14:01
Dr. Tom O’Bryan
Reduce the expression of rage? How do you calm that one down and you calm it down by reducing the production of advanced glycation end products. Stop eating French fries, stop eating deep fried foods, stop burning your meats.
01:16:14:18 – 01:16:15:03
Dr. Tom O’Bryan
You know.
01:16:15:16 – 01:16:29:01
Dr. Tom O’Bryan
Reduce your exposure to these high temperature cooked items. When oil smokes, when you’re frying and you use oil that smokes too late. When it smokes, it’s oxidized and it becomes.
01:16:31:16 – 01:16:32:04
Dr. Tom O’Bryan
It creates.
01:16:32:04 – 01:16:33:24
Dr. Tom O’Bryan
More advanced glycation end products.
01:16:34:18 – 01:16:43:09
Nathan Crane
Which are which are also directly responsible for damaging DNA, damaging and contributing to cancer cells. And. That’s right.
01:16:43:20 – 01:16:44:12
Dr. Tom O’Bryan
That’s exactly.
01:16:44:12 – 01:16:44:19
Dr. Tom O’Bryan
Right.
01:16:45:11 – 01:16:50:08
Dr. Tom O’Bryan
So I just wanted to include that one as a little bit of a bonus because it comes back positive.
01:16:50:15 – 01:16:52:04
Dr. Tom O’Bryan
Often for people. Hmm.
01:16:52:12 – 01:17:20:10
Nathan Crane
Yeah. And you can see I don’t eat much fried food at all. I saw today, I saw it in olive oil. And, you know, we get a really high quality, super clean olive oil. And I am mindful not to put the temperatures so high and we also don’t saute for super long. Right. But I rarely, rarely like once in a blue moon will eat something that’s been dropped in a deep fat fryer.
01:17:20:10 – 01:17:41:06
Nathan Crane
I mean, super, super rare. Or actually I have a barbecue and I’ve used it once in the last five years, you know, for special occasions. I think for Thanksgiving, I was like, Yeah, I’m going to barbecue up, you know? So sure, you know, but but yeah, it’s very, very rare with because of that exact reason of oil.
01:17:41:13 – 01:17:45:21
Dr. Tom O’Bryan
My suggestion is that people avoid sauteed and.
01:17:45:21 – 01:17:47:10
Dr. Tom O’Bryan
Olive oil and.
01:17:47:10 – 01:17:48:00
Dr. Tom O’Bryan
Rather.
01:17:48:08 – 01:17:55:02
Dr. Tom O’Bryan
Use avocado oil, coconut oil, which have a.
01:17:55:02 – 01:18:02:22
Dr. Tom O’Bryan
Higher smoking threshold and then pour high quality olive oil on the food just as you’re turning.
01:18:02:22 – 01:18:03:12
Dr. Tom O’Bryan
The heat off.
01:18:03:24 – 01:18:04:09
Nathan Crane
Yeah.
01:18:04:23 – 01:18:08:01
Dr. Tom O’Bryan
So you get all those polyphenols and all the great benefit.
01:18:08:14 – 01:18:09:02
Dr. Tom O’Bryan
Yeah.
01:18:09:02 – 01:18:29:14
Nathan Crane
Yeah, that’s a good point. Yeah. And that’s, and that’s, you know, and like I said, even when we cook with olive oil, yeah, we use coconut oil as well. Even when we cook with olive oil, it’s never, you know, so hot. It’s on a low, medium heat, right? The lower side. I never let it smoke. You know, it’s just more to kind of get get the flavor and that sort of thing.
01:18:29:14 – 01:18:31:24
Nathan Crane
But, you know, those simple things that you learn over.
01:18:32:05 – 01:18:34:01
Dr. Tom O’Bryan
Your hands when.
01:18:34:01 – 01:18:41:17
Dr. Tom O’Bryan
When someone has rage, antibodies elevated and they’re eating a diet as clean as yours and there’s.
01:18:41:17 – 01:18:42:05
Dr. Tom O’Bryan
No.
01:18:47:18 – 01:18:58:12
Dr. Tom O’Bryan
Hidden treats or cheat days or things like that. Some doctors say, well, have a cheat day once a week. That’s utter nonsense. Well, throw gasoline on the fire once a week.
01:18:58:19 – 01:19:00:14
Dr. Tom O’Bryan
All right. You know.
01:19:01:04 – 01:19:12:09
Dr. Tom O’Bryan
But when when someone’s rage antibodies are elevated, like here’s the next thing on the checklist that you look at is total tax burden. Are there toxins, heavy metals in your body.
01:19:12:21 – 01:19:13:02
Dr. Tom O’Bryan
That.
01:19:13:07 – 01:19:20:02
Dr. Tom O’Bryan
Activating that rage receptor so it could be lead mercury, arsenic, beryllium.
01:19:20:10 – 01:19:21:09
Dr. Tom O’Bryan
Could be mold.
01:19:21:19 – 01:19:42:00
Dr. Tom O’Bryan
So vibrant, a total tax burden test. You know, I took 27 patients in a row and I did seven tests on them before. I ever talked to them. I didn’t want to talk to them until they did the tests and they did these tests and the results were just jaw dropping.
01:19:42:00 – 01:19:43:17
Dr. Tom O’Bryan
Dramatic that.
01:19:43:17 – 01:19:45:24
Dr. Tom O’Bryan
We could just I met with them.
01:19:45:24 – 01:19:47:15
Dr. Tom O’Bryan
After that excuse me.
01:19:48:11 – 01:20:01:18
Dr. Tom O’Bryan
Got their history. They also sent me their last five years of test results. So I had all of that reviewed and I got together with them on Zoom and I said, Well, here’s your history, okay? And we did these two boom, boom.
01:20:01:18 – 01:20:02:17
Dr. Tom O’Bryan
Boom, boom, boom.
01:20:02:19 – 01:20:03:11
Dr. Tom O’Bryan
There it is.
01:20:04:09 – 01:20:05:19
Dr. Tom O’Bryan
It’s all done. You know.
01:20:06:00 – 01:20:09:15
Dr. Tom O’Bryan
This is certainly where you have to spark start. These are.
01:20:09:15 – 01:20:10:16
Dr. Tom O’Bryan
The major.
01:20:11:19 – 01:20:15:03
Dr. Tom O’Bryan
Inflammatory three triggers in your lifestyle.
01:20:15:03 – 01:20:15:16
Dr. Tom O’Bryan
Right now.
01:20:16:04 – 01:20:35:12
Dr. Tom O’Bryan
And out of 27 people, probably I haven’t really counted it up, but probably 23 or 24 of them was toxic chemicals, heavy metals, acute and food sensitivities, three or four of them. It was emotional stress and trauma and excess stress hormones.
01:20:35:24 – 01:20:36:07
Dr. Tom O’Bryan
And I had.
01:20:36:07 – 01:20:38:11
Dr. Tom O’Bryan
To refer them, you know, for some counseling.
01:20:39:06 – 01:20:39:11
Dr. Tom O’Bryan
To.
01:20:39:11 – 01:20:42:00
Dr. Tom O’Bryan
Include in their protocol. But for the majority.
01:20:42:00 – 01:20:43:01
Dr. Tom O’Bryan
Of them, we.
01:20:43:01 – 01:20:46:10
Dr. Tom O’Bryan
Nailed it right away. And the results have been dramatic since then.
01:20:46:10 – 01:20:48:18
Dr. Tom O’Bryan
For them, they’re all very grateful.
01:20:49:14 – 01:21:25:08
Nathan Crane
Yeah, I imagine some of the it be interesting to see I’ll redo this test in a period of time. Right. In six months. Yeah. Because I had already, you know, I was training to be a professional athlete and I, I went to too many injuries to the point where I finally stopped and that was, I think January, February, January, February, March of this year, where I finally took a big step back and reduced everything significantly and really started focusing on healing my body.
01:21:25:08 – 01:21:46:23
Nathan Crane
I was training 5 hours a day. Yeah. You know, anywhere from two and a half to 3 to 5 hours a day for less, almost seven years. And so the moment I did that right, like a lot of my inflammatory markers through my other blood tests that I had done, you know, after three months of like just reducing that, all of that went down substantially.
01:21:47:06 – 01:22:09:02
Nathan Crane
And so this was July we did this test that was in February, March, it May, June, July. Yeah. Be interesting to see how much of these things are impacted, you know, by me taking a step back from because that amount of training, you’re just, you know, I’m doing all these things to help my body, you know, combat the damage I’m doing through that training.
01:22:09:02 – 01:22:22:03
Nathan Crane
Yeah, but there’s still going to be higher elevations of, you know, in flat inflammation and immune system struggling to try to, you know, keep up with something like that, cysteine bar and streptococcal and that kind of stuff.
01:22:22:03 – 01:22:27:24
Dr. Tom O’Bryan
Well, yeah. And you’ve you’ve seen the studies where intense training creates leaky gut immediately.
01:22:29:01 – 01:22:31:05
Dr. Tom O’Bryan
Immediately, you know, and then all.
01:22:31:05 – 01:22:33:16
Dr. Tom O’Bryan
The cascade effects of that one. So that’s great.
01:22:33:16 – 01:23:01:11
Nathan Crane
That, that I should have been sleeping ten or 11 hours with how much training I was doing and I was only sleeping, you know, seven seven or eight, which is great for a normal person who’s not training 5 hours a day, you know. And so not enough sleep, overtraining, you know, end up with injuries and. Yeah, but anyway, so on some of these things like what are our next steps, brain inflammation aside from I’m already doing right of reduced training.
01:23:01:17 – 01:23:02:08
Dr. Tom O’Bryan
You know what.
01:23:02:08 – 01:23:06:07
Dr. Tom O’Bryan
What would be interesting and it’s really an academic.
01:23:06:07 – 01:23:08:04
Dr. Tom O’Bryan
Point but.
01:23:08:04 – 01:23:29:05
Dr. Tom O’Bryan
Because you’re in the business you might want to redo the neural zoomer plus now and see because you’ve changed your life in the last three months, you’re not training so hard. And was it the training that produced some of this response. Mm. That, that would be interesting because your diet sounds very clean. Well why do the rage antibodies there.
01:23:29:05 – 01:23:33:00
Nathan Crane
Well ah you said the rage antibodies aren’t on mine. Those are in the green.
01:23:33:22 – 01:23:34:12
Dr. Tom O’Bryan
Oh that’s right.
01:23:35:19 – 01:23:36:02
Dr. Tom O’Bryan
Sorry.
01:23:36:14 – 01:23:37:04
Dr. Tom O’Bryan
I guess so.
01:23:37:04 – 01:23:39:15
Dr. Tom O’Bryan
Part I, I get caught in there.
01:23:39:15 – 01:23:40:21
Dr. Tom O’Bryan
Once I get started.
01:23:40:21 – 01:23:41:04
Dr. Tom O’Bryan
You’re right.
01:23:41:16 – 01:23:50:18
Nathan Crane
No, but, but the other ones, the inflammation, the, the infections right, the other markers. Yeah.
01:23:50:22 – 01:23:51:06
Dr. Tom O’Bryan
Yeah.
01:23:51:13 – 01:23:56:11
Dr. Tom O’Bryan
Was your training suppressing your immune system so that it couldn’t deal.
01:23:56:11 – 01:23:58:13
Dr. Tom O’Bryan
With what what.
01:23:58:13 – 01:24:00:14
Dr. Tom O’Bryan
Viruses you’ve had you have in your body?
01:24:00:19 – 01:24:01:01
Dr. Tom O’Bryan
Yeah.
01:24:01:01 – 01:24:05:13
Dr. Tom O’Bryan
And is it better now? I mean, that that’s an academic question. Before you do anything else.
01:24:06:00 – 01:24:08:07
Dr. Tom O’Bryan
It might be useful.
01:24:08:07 – 01:24:12:15
Dr. Tom O’Bryan
For you because you’re going to be working with professional athletes for your entire career.
01:24:13:03 – 01:24:13:16
Dr. Tom O’Bryan
And if.
01:24:13:16 – 01:24:14:20
Dr. Tom O’Bryan
You can show.
01:24:15:00 – 01:24:15:20
Dr. Tom O’Bryan
Now.
01:24:16:10 – 01:24:24:08
Dr. Tom O’Bryan
Look, I just stopped training three months. I did this test and I changed my training routine and look at three months later.
01:24:25:05 – 01:24:25:16
Dr. Tom O’Bryan
Without.
01:24:25:16 – 01:24:29:00
Dr. Tom O’Bryan
Doing anything else.
01:24:29:00 – 01:24:34:02
Nathan Crane
It’s a great idea. Yeah, I’ll probably redo the test then I want to do the the fingerprints.
01:24:34:02 – 01:24:35:24
Dr. Tom O’Bryan
So it’s an easy, easy thing to do.
01:24:36:03 – 01:25:04:07
Nathan Crane
Yeah. And then in terms of the gluten, so I rarely ever eat gluten and you know, most thing I know gluten can end up in almost everything and so many things. But we’re very mindful about gluten, gluten, bread, you know, any kind of wheat certified gluten free products. So like we I mean, I stopped eating gluten years ago and I’ll have some once in a while.
01:25:04:09 – 01:25:09:19
Nathan Crane
But you said the or these are in the moderate category just so I.
01:25:09:19 – 01:25:12:24
Dr. Tom O’Bryan
Know those and cerebellum cerebellum and fricking.
01:25:13:14 – 01:25:13:24
Dr. Tom O’Bryan
And.
01:25:14:08 – 01:25:17:13
Nathan Crane
And those are directly related to gluten.
01:25:17:13 – 01:25:23:16
Dr. Tom O’Bryan
That’s the most common it’s the most common trigger. Now, what what you have to understand.
01:25:24:05 – 01:25:25:04
Dr. Tom O’Bryan
About wheat.
01:25:25:09 – 01:25:34:24
Dr. Tom O’Bryan
Is that once your immune system has elevated antibodies to the peptides of wheat, you create memory B cells.
01:25:35:04 – 01:25:40:18
Dr. Tom O’Bryan
Mm hmm. Now When you got a shot.
01:25:40:18 – 01:25:44:02
Dr. Tom O’Bryan
Of vaccination for measles as a kid.
01:25:44:22 – 01:25:47:04
Dr. Tom O’Bryan
They gave you the bug measles.
01:25:48:03 – 01:26:13:05
Dr. Tom O’Bryan
And you’re. And the brain says, Whoa, what’s this in the bloodstream that’s not supposed to be there, you general. And then your immune cells and, you’ve got Army, Air Force, Marine Corps generals sitting around with nothing to do. General, you now are general measles. Take care of this. General measles builds an assembly line. The assembly line starts producing soldiers, highly trained specific special forces.
01:26:13:17 – 01:26:36:05
Dr. Tom O’Bryan
They’re called antibodies and they go after measles, nothing else. They look for the protein structure like a vest. I call it the orange vest, like a hunter wears an orange vest. Well, they look for the amino acid structure of measles and they going through the bloodstream, firing their chemical bullets everywhere when they.
01:26:36:05 – 01:26:36:20
Dr. Tom O’Bryan
Kill.
01:26:37:17 – 01:26:38:22
Dr. Tom O’Bryan
All of the measles.
01:26:38:22 – 01:26:40:07
Dr. Tom O’Bryan
Bug from.
01:26:40:07 – 01:27:09:16
Dr. Tom O’Bryan
The vaccination. General measles, who’s watching all this, says, okay turn off the assembly line. We don’t need more soldiers here right now. And that process takes about two months, three months when we get a vaccination. But now, General, measles is vigilant the rest of his life and he’s dormant. He’s like the soldiers of Buckingham Palace. He doesn’t do anything.
01:27:09:16 – 01:27:35:07
Dr. Tom O’Bryan
He’s dormant. But if I’m on a plane and the guy in front of me coughs into the air measles bug because he just came back from Mozambique and I inhale measles, but now it’s in my bloodstream. General measles sees this. He doesn’t have to take two months to build the assembly line. He just has to flip the switch and the antibodies are there.
01:27:35:07 – 01:27:35:16
Dr. Tom O’Bryan
The next.
01:27:35:16 – 01:27:36:14
Dr. Tom O’Bryan
Day.
01:27:36:14 – 01:27:38:22
Dr. Tom O’Bryan
And it takes care of whatever I’m exposed to.
01:27:38:22 – 01:27:39:13
Dr. Tom O’Bryan
And I’m fine.
01:27:40:02 – 01:27:42:13
Dr. Tom O’Bryan
That’s how vaccinations are supposed to work.
01:27:43:04 – 01:27:43:11
Dr. Tom O’Bryan
Right?
01:27:43:18 – 01:27:46:06
Nathan Crane
Right. Keyword supposed, supposed to. Yeah.
01:27:46:17 – 01:27:51:10
Dr. Tom O’Bryan
Right. Right now the only food that I can.
01:27:51:10 – 01:27:53:15
Dr. Tom O’Bryan
Find science.
01:27:53:15 – 01:27:54:00
Dr. Tom O’Bryan
On.
01:27:54:21 – 01:27:57:03
Dr. Tom O’Bryan
Memory B cells is gluten.
01:27:57:13 – 01:27:57:22
Dr. Tom O’Bryan
Mm.
01:27:58:07 – 01:28:13:07
Dr. Tom O’Bryan
There are no memory B cells to dairy. There are no memory B cells to soy or to mayo. That’s why you probably can eat them sometime in the future. But. But gluten. Absolutely not. Because a morsel and it takes an eighth.
01:28:13:07 – 01:28:14:07
Dr. Tom O’Bryan
Of a thumbnail.
01:28:14:23 – 01:28:17:18
Dr. Tom O’Bryan
An eighth of a that’s all it takes is a morsel.
01:28:18:07 – 01:28:18:20
Dr. Tom O’Bryan
And.
01:28:19:16 – 01:28:21:14
Dr. Tom O’Bryan
General gluten flips the.
01:28:21:14 – 01:28:23:17
Dr. Tom O’Bryan
Switch and now for.
01:28:23:21 – 01:28:46:14
Dr. Tom O’Bryan
2 to 4 months because the the the assembly line is on for 6 to 8 weeks and then the antibodies that are produced towards the end of that 6 to 8 weeks have a life span of 5 to 7, 5 to 8 weeks. So you’ve got 3 to 4 months of antibodies from single exposure.
01:28:46:23 – 01:28:51:23
Nathan Crane
Which means you have 3 to 4 months of additional inflammation happening in the body.
01:28:52:05 – 01:29:01:05
Dr. Tom O’Bryan
Additional inflammation. But for you lightly additional cerebellar antibodies and parkin g cell antibodies attacking your brain.
01:29:01:11 – 01:29:01:24
Dr. Tom O’Bryan
Mm.
01:29:02:18 – 01:29:03:18
Dr. Tom O’Bryan
Because of molecular.
01:29:03:18 – 01:29:06:03
Dr. Tom O’Bryan
Mimicry.
01:29:06:03 – 01:29:08:01
Dr. Tom O’Bryan
You can’t be a little pregnant.
01:29:08:16 – 01:29:10:07
Dr. Tom O’Bryan
You can’t have a little gluten.
01:29:11:19 – 01:29:26:12
Nathan Crane
I can’t be a little pregnant anyway, but. Oh, yeah, this is great. I know we’re out of time, so how can people get these tests for themselves? Do you?
01:29:26:12 – 01:29:48:18
Dr. Tom O’Bryan
It’s really a good question. You know, I’ve got this whole thing set up now because I think this is so primary for everyone. If you go to the D.R. dot com, the doctor dot com, just don’t spell the word doctor of the Dr. dot com forward slash health span dash voice life health span dash versus dash life span.
01:29:49:10 – 01:29:50:13
Dr. Tom O’Bryan
It’s all there for.
01:29:50:13 – 01:29:51:11
Dr. Tom O’Bryan
You all.
01:29:51:11 – 01:30:03:03
Dr. Tom O’Bryan
About the neural zoomers. Plus, this is all about extending your healthy life span closer to your total lifespan. That’s the goal. And the first step.
01:30:03:18 – 01:30:04:19
Dr. Tom O’Bryan
Is to and.
01:30:05:12 – 01:30:07:08
Nathan Crane
It’s not pulling up the.
01:30:08:02 – 01:30:09:00
Dr. Tom O’Bryan
ABC or.
01:30:09:00 – 01:30:11:10
Nathan Crane
Our Dr. dot com for.
01:30:11:14 – 01:30:18:17
Dr. Tom O’Bryan
Healthspan dash v. S versus vs dash lifespan.
01:30:20:07 – 01:30:24:08
Nathan Crane
Healthspan dash vs dash lifespan. Okay.
01:30:24:09 – 01:30:24:21
Dr. Tom O’Bryan
Yes.
01:30:26:01 – 01:30:27:00
Nathan Crane
It’s kind of a long one.
01:30:27:17 – 01:30:29:11
Dr. Tom O’Bryan
And I know I said, what?
01:30:31:01 – 01:30:32:12
Dr. Tom O’Bryan
There you go. There it is.
01:30:32:19 – 01:30:35:11
Nathan Crane
So this is where they can get all the details about it and get the test.
01:30:35:13 – 01:30:54:03
Dr. Tom O’Bryan
Yeah. Yeah. And there is the Blue Cross Blue Shield study if you want to scroll down there to that one to take a look at that for just a moment. Right there. Right there. That’s it. And look at that 30 to 44 age bracket right there, 373% increase.
01:30:54:15 – 01:30:56:07
Nathan Crane
Yes, early in.
01:30:56:07 – 01:30:57:04
Dr. Tom O’Bryan
Four years.
01:30:57:04 – 01:31:16:14
Nathan Crane
And on I was my neighbor. This just is, I think, late, late sixties, early seventies. Just I found his wife bringing him from the hospital the other day in a wheelchair, trying to get him in the house. And he was trying to get out of the wheelchair and she was trying to keep him in it. And he was a fall risk.
01:31:16:14 – 01:31:41:02
Nathan Crane
And I was thankfully, I was walking back home from a walk. I’ve been walking now after I eat and doing kind of a meditative walk and listening to spiritual programs. And I’m walking back home and I see her struggling and I just walk over there and help her get him into the house. And he’s so discombobulated, doesn’t really know where he is.
01:31:41:02 – 01:32:02:16
Nathan Crane
He thinks the pictures on the wall are him and his brothers and his wife’s telling me, no, those are our sons, our three sons. You know, he was really and I said, when did this oh, it’s only been a couple of weeks, you know, but over the months, little things started happening. You kind of forgot where he was driving to or things like that popping up.
01:32:02:16 – 01:32:17:23
Nathan Crane
And now it’s like looks like full blown Alzheimer’s or dementia, you know, couldn’t remember anything. He just didn’t really know who anybody was. And it was really extreme to see that and very sad to see that.
01:32:18:10 – 01:32:26:15
Dr. Tom O’Bryan
Yeah, it happened to my mother also. And wasn’t Alzheimer’s is. But sepsis. Sepsis will cause those kinds of hallucinations and.
01:32:27:06 – 01:32:28:21
Dr. Tom O’Bryan
And that’s.
01:32:28:21 – 01:32:29:23
Dr. Tom O’Bryan
A whole nother discussion.
01:32:29:23 – 01:32:30:24
Dr. Tom O’Bryan
But yeah.
01:32:30:24 – 01:32:48:12
Nathan Crane
But just point being is like it, you know, she said it was normal up until boom then all of a sudden and little things happening over the time and then now. Right it’s like it seems like it came out of nowhere. But no, just as you said, it’s been going on for decades under the hood of chronic inflammation.
01:32:48:12 – 01:33:08:04
Nathan Crane
Yeah. So yeah so after they go, so if people go through this, get the testing and then do you give people do they get support from your team on. Yes, yes. And in the test and then what to do about it, what to clean up in the diet. Yeah. All that kind of stuff. Yeah.
01:33:08:19 – 01:33:12:18
Dr. Tom O’Bryan
Yeah. Okay. Yeah. I think, I think.
01:33:12:18 – 01:33:14:19
Dr. Tom O’Bryan
That this is such a priority.
01:33:15:15 – 01:33:19:13
Dr. Tom O’Bryan
I’m dedicating my professional career for the.
01:33:19:13 – 01:33:21:13
Dr. Tom O’Bryan
Next three years to this.
01:33:21:13 – 01:33:22:02
Dr. Tom O’Bryan
Topic.
01:33:22:15 – 01:33:30:20
Dr. Tom O’Bryan
And I want to carry this message all over the world that people just start looking to see what’s under the surface, what’s under the hood.
01:33:31:05 – 01:33:32:22
Dr. Tom O’Bryan
What’s going on right now.
01:33:33:13 – 01:33:36:05
Dr. Tom O’Bryan
And then they can start addressing whatever it is.
01:33:36:05 – 01:33:36:23
Dr. Tom O’Bryan
That they find.
01:33:38:01 – 01:34:01:02
Nathan Crane
Beautiful. Well, Doctor, I appreciate you taking the time. This has been incredibly valuable. I think people get a ton of value out of this. I think the test is something everybody should do and see where you’re at. No your age and see what you have to work on. There’s always something to work on. Right. And I’m glad to see that, you know, this is one of the best first you’ve ever had anybody send in.
01:34:01:02 – 01:34:09:23
Nathan Crane
So what I’ve been doing and what we teach obviously works, you know, and there’s things to improve upon, right? So appreciate appreciate you taking the time.
01:34:10:20 – 01:34:12:16
Dr. Tom O’Bryan
My pleasure. Really, my pleasure.
01:34:13:02 – 01:34:15:10
Dr. Tom O’Bryan
Once again, congratulations. You’re doing great.
01:34:15:10 – 01:34:17:08
Dr. Tom O’Bryan
The things you’re working on. And now, now you.
01:34:17:08 – 01:34:20:10
Dr. Tom O’Bryan
Can look at those little things that are under the surface.
01:34:20:10 – 01:34:23:23
Nathan Crane
They’re awesome. All right. Thanks. Take care.
01:34:23:24 – 01:34:25:03
Dr. Tom O’Bryan
All right. Take care.